Sitagliptin N-Acetyl Impurity

Name: Sitagliptin N-Acetyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-005936

About Sitagliptin N-Acetyl Impurity

Sitagliptin N-Acetyl Impurity (CAS 1379666-94-0) is an impurity of Sitagliptin offered by Vaqora Chemicals with a typical assay of 98%. Its molecular formula is C18H17F6N5O2 and its molecular weight is 449.3 g/mol. Alternative names: N-Acetyl Sitagliptin and N-Acetylsitagliptin.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Sitagliptin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sitagliptin N-Acetyl Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin N-Acetyl Impurity
Catalogue No.	VQ-005936
CAS Number	1379666-94-0
IUPAC name	N-[(2R)-4-oxo-4-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]acetamide
Molecular formula	C₁₈H₁₇F₆N₅O₂
Molecular weight	449.3 g/mol
Exact mass	449.1286
Grade	Reference Standard
Purity / assay	98%
HSN code	38229090
InChIKey	YGFMQPHTQKCJPI-LLVKDONJSA-N
SMILES	CC(=O)N[C@H](CC1=CC(=C(C=C1F)F)F)CC(=O)N2CCN3C(=NN=C3C(F)(F)F)C2
PubChem CID	54764463

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	1 / 10
TPSA	80.1 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin N-Acetyl Impurity?

The CAS Registry Number of Sitagliptin N-Acetyl Impurity is 1379666-94-0. It is also known as N-Acetyl Sitagliptin, N-Acetylsitagliptin.

What is the molecular formula and molecular weight of Sitagliptin N-Acetyl Impurity?

Sitagliptin N-Acetyl Impurity has the molecular formula C18H17F6N5O2 and a molecular weight of 449.3 g/mol. Its IUPAC name is N-[(2R)-4-oxo-4-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]acetamide.

What is Sitagliptin N-Acetyl Impurity used for?

Sitagliptin N-Acetyl Impurity is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin N-Acetyl Impurity can I order?

We supply Sitagliptin N-Acetyl Impurity in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin N-Acetyl Impurity?

Yes. Every lot of Sitagliptin N-Acetyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin N-Acetyl Impurity be shipped internationally?

Yes. Sitagliptin N-Acetyl Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.