Sodium Cromoglicate EP Impurity B

Name: Sodium Cromoglicate EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-028066

About Sodium Cromoglicate EP Impurity B

Listed under CAS 16150-45-1, Sodium Cromoglicate EP Impurity B is a pharmacopeial impurity of Cromolyn available from Vaqora Chemicals. Its molecular formula is C27H24O11 and its molecular weight is 524.5 g/mol. The IUPAC name is ethyl 5-[3-(2-ethoxycarbonyl-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate. Common synonyms include Cromolyn USP Related Compound B and Sodium Cromoglicate - Impurity B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Cromolyn to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sodium Cromoglicate EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cromolyn

View every impurity, metabolite and intermediate we list for Cromolyn.

Cromolyn impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sodium Cromoglicate EP Impurity B
Catalogue No.	VQ-028066
CAS Number	16150-45-1
IUPAC name	ethyl 5-[3-(2-ethoxycarbonyl-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate
Molecular formula	C₂₇H₂₄O₁₁
Molecular weight	524.5 g/mol
Exact mass	524.1319
Grade	Reference Standard
HSN code	38229090
InChIKey	KRBBSLDXYDBFEC-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=CC(=O)C2=C(O1)C=CC=C2OCC(COC3=CC=CC4=C3C(=O)C=C(O4)C(=O)OCC)O
PubChem CID	204318

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	1 / 11
TPSA	144 Å²
Synonyms	Cromolyn USP Related Compound B, Sodium Cromoglicate - Impurity B, Diethyl cromoglycate, Diethyl 5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate), Cromophene, Cromoglycic acid diethyl ester, Diethyl 5,5'-((2-hydroxypropane-1,3-diyl)-bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate), Diethyl5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate), Diethyl 5,5'-[(2-hydroxypropane-1,3-diyl)bis(oxy)]bis(4-oxo-4H-1-benzopyran-2-carboxylate)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sodium Cromoglicate EP Impurity B?

The CAS Registry Number of Sodium Cromoglicate EP Impurity B is 16150-45-1. It is also known as Cromolyn USP Related Compound B, Sodium Cromoglicate - Impurity B, Diethyl cromoglycate.

What is the molecular formula and molecular weight of Sodium Cromoglicate EP Impurity B?

Sodium Cromoglicate EP Impurity B has the molecular formula C27H24O11 and a molecular weight of 524.5 g/mol. Its IUPAC name is ethyl 5-[3-(2-ethoxycarbonyl-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate.

What is Sodium Cromoglicate EP Impurity B used for?

Sodium Cromoglicate EP Impurity B is supplied as a characterised reference material related to Cromolyn. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sodium Cromoglicate EP Impurity B can I order?

We supply Sodium Cromoglicate EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sodium Cromoglicate EP Impurity B?

Yes. Every lot of Sodium Cromoglicate EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sodium Cromoglicate EP Impurity B be shipped internationally?

Yes. Sodium Cromoglicate EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.