Sofosbuvir 3'-O-Phosphoramidate

Name: Sofosbuvir 3'-O-Phosphoramidate
Brand: Vaqora Chemicals
SKU: VQ-023778

About Sofosbuvir 3'-O-Phosphoramidate

Vaqora Chemicals supplies Sofosbuvir 3'-O-Phosphoramidate, an impurity of Sofosbuvir registered under CAS number 1337482-15-1. Its molecular formula is C22H29FN3O9P and its molecular weight is 529.5 g/mol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Sofosbuvir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Sofosbuvir 3'-O-Phosphoramidate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sofosbuvir

View every impurity, metabolite and intermediate we list for Sofosbuvir.

Sofosbuvir impurities

Specifications & identifiers

Chemical identifiers
Product name	Sofosbuvir 3'-O-Phosphoramidate
Catalogue No.	VQ-023778
CAS Number	1337482-15-1
IUPAC name	propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-yl]oxy-phenoxyphosphoryl]amino]propanoate
Molecular formula	C₂₂H₂₉FN₃O₉P
Molecular weight	529.5 g/mol
Exact mass	529.1625
Grade	Reference Standard
HSN code	38229090
InChIKey	IBMLPFZASPUMOW-IAAJYNJHSA-N
SMILES	C[C@@H](C(=O)OC(C)C)NP(=O)(O[C@@H]1[C@H](O[C@H]([C@]1(C)F)N2C=CC(=O)NC2=O)CO)OC3=CC=CC=C3
PubChem CID	58463528

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	3 / 11
TPSA	153 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sofosbuvir 3'-O-Phosphoramidate?

The CAS Registry Number of Sofosbuvir 3'-O-Phosphoramidate is 1337482-15-1. It is also known as Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate].

What is the molecular formula and molecular weight of Sofosbuvir 3'-O-Phosphoramidate?

Sofosbuvir 3'-O-Phosphoramidate has the molecular formula C22H29FN3O9P and a molecular weight of 529.5 g/mol. Its IUPAC name is propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-yl]oxy-phenoxyphosphoryl]amino]propanoate.

What is Sofosbuvir 3'-O-Phosphoramidate used for?

Sofosbuvir 3'-O-Phosphoramidate is supplied as a characterised reference material related to Sofosbuvir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sofosbuvir 3'-O-Phosphoramidate can I order?

We supply Sofosbuvir 3'-O-Phosphoramidate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sofosbuvir 3'-O-Phosphoramidate?

Yes. Every lot of Sofosbuvir 3'-O-Phosphoramidate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sofosbuvir 3'-O-Phosphoramidate be shipped internationally?

Yes. We export Sofosbuvir 3'-O-Phosphoramidate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.