((2R,3R,4R,5R)-3-(Benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl Benzoate
- CAS
- 863329-65-1
- Formula
- C24H21FN2O7
- MW
- 468.4 g/mol
VQ-028071
Impurity reference standards
Sofosbuvir impurities & reference standards
Characterised Sofosbuvir impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.
53reference materials
1isotope-labelled
COAHPLC · NMR · MS on request
((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl dihydrogen Phosphate
- CAS
- 1015073-43-4
- Formula
- C10H14FN2O8P
- MW
- 340.2 g/mol
VQ-028068
((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl Phenyl Hydrogen Phosphate
- CAS
- 1859162-80-3
- Formula
- C16H18FN2O8P
- MW
- 416.29 g/mol
VQ-023779
((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl Benzoate
- CAS
- 874638-80-9
- Formula
- C20H17FO6
- MW
- 372.3 g/mol
VQ-033898
((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-Methyltetrahydrofuran-2-yl)Methyl benzoate
- CAS
- 1884385-12-9
- Formula
- C20H19FO6
- MW
- 374.4 g/mol
VQ-042216
((2R,3R,4R)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-Methyltetrahydrofuran-2-yl)Methyl benzoate
- CAS
- 1621160-31-3
- Formula
- C20H18ClFO5
- MW
- 392.8 g/mol
VQ-042217
(2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-chloro-4-methyltetrahydrofuran-3-yl benzoate
- CAS
- 1496551-70-2
- Formula
- C31H26ClN3O7
- MW
- 588 g/mol
VQ-044020
(2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate
- CAS
- 817204-32-3
- Formula
- C31H26FN3O7
- MW
- 571.6 g/mol
VQ-023785
(2R)-2-Deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl Chloride 3,5-Dibenzoate
- CAS
- 1199809-23-8
- Formula
- C20H18ClFO5
- MW
- 392.8 g/mol
VQ-043301
(2S,3R)-Ethyl 3-((R)-2,2-Dimethyl-1,3-Dioxolan-4-yl)-2,3-Dihydroxy-2-Methylpropanoate
- CAS
- 93635-76-8
- Formula
- C11H20O6
- MW
- 248.27 g/mol
VQ-043304
(2S)-Isopropyl-2-(((((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methylenetetrahydrofuran-2-yl)methoxy (phenoxy)phosphoryl)amino)propanoate
- CAS
- 2095551-20-3
- Formula
- C22H28N3O9P
- MW
- 509.4 g/mol
VQ-023781
(3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one
- CAS
- 879551-04-9
- Formula
- C6H9FO4
- MW
- 164.13 g/mol
VQ-042219
(4S,5R)-Ethyl 5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-methyl-1,3,2-dioxathiolane-4-carboxylate 2,2-dioxide
- CAS
- 879551-01-6
- Formula
- C11H18O8S
- MW
- 310.32 g/mol
VQ-033903
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
- CAS
- 15186-48-8
- Formula
- C6H10O3
- MW
- 130.14 g/mol
VQ-030964
(S,E)-Ethyl 3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylacrylate
- CAS
- 81997-76-4
- Formula
- C11H18O4
- MW
- 214.26 g/mol
VQ-043305
1-((2S,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
- CAS
- 2041584-99-8
- Formula
- C10H13FN2O5
- MW
- 260.22 g/mol
VQ-028069
Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-D-alaninate
- CAS
- 1627824-09-2
- Formula
- C18H17F5NO5P
- MW
- 453.3 g/mol
VQ-033900
![Isopropyl N-[chloro(phenoxy)phosphoryl]-L-alaninate chemical structure](/media/structures/SKAAFTUHFLUIKV-IHBJSSOOSA-N.svg)
Isopropyl N-[chloro(phenoxy)phosphoryl]-L-alaninate
- CAS
- 261909-49-3
- Formula
- C12H17ClNO4P
- MW
- 305.69 g/mol
VQ-042221
![N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-D-alanine-1-methylethyl ester chemical structure](/media/structures/MIILDBHEJQLACD-QVRUCNGISA-N.svg)
N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-D-alanine-1-methylethyl ester
- CAS
- 1714114-25-6
- Formula
- C18H17F5NO5P
- MW
- 453.3 g/mol
VQ-028072
Sofosbuvir Impurity, 1-β-D-Arabinofuranosyluracil-2-C-methyl
- CAS
- 114262-49-6
- Formula
- C10H14N2O6
- MW
- 258.23 g/mol
VQ-045351
Sofosbuvir L-alanitate (Mixture of Diasteriomers)
- CAS
- 1064684-44-1
- Formula
- C22H29FN3O9P
- MW
- 529.5 g/mol
VQ-033895
FAQs — Sofosbuvir impurities
Which Sofosbuvir impurities do you supply?
We list 53 Sofosbuvir-related reference materials, including process impurities, degradation products, stable-isotope-labelled standards and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.
What are Sofosbuvir impurity standards used for?
They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).
Can you synthesise a Sofosbuvir impurity that is not listed?
Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.
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