Sotalol EP Impurity B

Name: Sotalol EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-033931

About Sotalol EP Impurity B

Sotalol EP Impurity B (CAS 60735-85-5) is a pharmacopeial impurity of Sotalol offered by Vaqora Chemicals. Its molecular formula is C12H18N2O3S and its molecular weight is 270.35 g/mol. Its systematic (IUPAC) name is N-[4-[2-(propan-2-ylamino)acetyl]phenyl]methanesulfonamide. It is also known as Sotalol Hydrochloride - Impurity B (Freebase) or Oxo sotalol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Sotalol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sotalol EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Sotalol

View every impurity, metabolite and intermediate we list for Sotalol.

Sotalol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sotalol EP Impurity B
Catalogue No.	VQ-033931
CAS Number	60735-85-5
IUPAC name	N-[4-[2-(propan-2-ylamino)acetyl]phenyl]methanesulfonamide
Molecular formula	C₁₂H₁₈N₂O₃S
Molecular weight	270.35 g/mol
Exact mass	270.1038
Grade	Reference Standard
HSN code	38229090
InChIKey	BKXGLPPAZWSLEH-UHFFFAOYSA-N
SMILES	CC(C)NCC(=O)C1=CC=C(C=C1)NS(=O)(=O)C
PubChem CID	11086835

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	2 / 5
TPSA	83.7 Å²
Synonyms	Sotalol Hydrochloride - Impurity B (Freebase), Oxo sotalol, N-(4-(((1-Methylethyl)amino)acetyl)phenyl)methanesulfonamide, Methanesulfonamide, N-(4-(2-((1-methylethyl)amino)acetyl)phenyl)-, Sotalol hydrochloride specified impurity B, N-(4-(2-(Isopropylamino)acetyl)phenyl)methanesulfonamide, N-[4-[2-(isopropylamino)acetyl]phenyl]methanesulfonamide, N-[4-[2-[(1-Methylethyl)amino]acetyl]phenyl]Methane Sulfonamide, N-{4-[N-(Propan-2-yl)glycyl]phenyl}methanesulfonamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements: P264 + P265, P280, P305 + P351 + P338, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sotalol EP Impurity B?

The CAS Registry Number of Sotalol EP Impurity B is 60735-85-5. It is also known as Sotalol Hydrochloride - Impurity B (Freebase), Oxo sotalol, N-(4-(((1-Methylethyl)amino)acetyl)phenyl)methanesulfonamide.

What is the molecular formula and molecular weight of Sotalol EP Impurity B?

Sotalol EP Impurity B has the molecular formula C12H18N2O3S and a molecular weight of 270.35 g/mol. Its IUPAC name is N-[4-[2-(propan-2-ylamino)acetyl]phenyl]methanesulfonamide.

What is Sotalol EP Impurity B used for?

Sotalol EP Impurity B is supplied as a characterised reference material related to Sotalol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sotalol EP Impurity B can I order?

We supply Sotalol EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sotalol EP Impurity B?

Yes. Every lot of Sotalol EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sotalol EP Impurity B be shipped internationally?

Yes. Sotalol EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.