(S,S)-Palonosetron Hydrochloride

Name: (S,S)-Palonosetron Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-004286

About (S,S)-Palonosetron Hydrochloride

Vaqora Chemicals supplies (S,S)-Palonosetron Hydrochloride, an impurity of Palonosetron registered under CAS number 135729-62-3. With the molecular formula C19H25ClN2O, it has a molar mass of 332.9 g/mol. Systematically, it is named (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one. Hydrochloride. Alternative names: Aloxi and Onicit.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

This Palonosetron impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (S,S)-Palonosetron Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Palonosetron

View every impurity, metabolite and intermediate we list for Palonosetron.

Palonosetron impurities

Specifications & identifiers

Chemical identifiers
Product name	(S,S)-Palonosetron Hydrochloride
Catalogue No.	VQ-004286
CAS Number	135729-62-3
Other CAS	135729-61-2, 1021481-17-3
IUPAC name	(3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;hydrochloride
Molecular formula	C₁₉H₂₅ClN₂O
Molecular weight	332.9 g/mol
Exact mass	332.1655
Grade	Reference Standard
HSN code	38229090
InChIKey	OLDRWYVIKMSFFB-SSPJITILSA-N
SMILES	C1C[C@@H]2CN(C(=O)C3=CC=CC(=C23)C1)[C@@H]4CN5CCC4CC5.Cl
PubChem CID	6918303

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 2
TPSA	23.6 Å²
Synonyms	(S,S)-Palonosetron Hydrochloride, Aloxi, Onicit, Palonosetron hydrochloride, PALONOSETRON HCl, Palonocetron hydrochloride, Palonosetron (as hydrochloride), Palonsetron hydrochloride, Palonosetron (Hydrochloride), Aloxi (TN), Palonosetron hydrochloride (Aloxi), C19H25ClN2O

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 135729-62-3

Palonosetron hydrochloride, 98%

CAS: 135729-62-3
Formula: C₁₉H₂₅ClN₂O
MW: 332.9 g/mol

VQ-012525

Frequently asked questions

What is the CAS number of (S,S)-Palonosetron Hydrochloride?

The CAS Registry Number of (S,S)-Palonosetron Hydrochloride is 135729-62-3. It is also known as (S,S)-Palonosetron Hydrochloride, Aloxi, Onicit.

What is the molecular formula and molecular weight of (S,S)-Palonosetron Hydrochloride?

(S,S)-Palonosetron Hydrochloride has the molecular formula C19H25ClN2O and a molecular weight of 332.9 g/mol.

What is (S,S)-Palonosetron Hydrochloride used for?

(S,S)-Palonosetron Hydrochloride is supplied as a characterised reference material related to Palonosetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S,S)-Palonosetron Hydrochloride can I order?

We supply (S,S)-Palonosetron Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S,S)-Palonosetron Hydrochloride?

Yes. Every lot of (S,S)-Palonosetron Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S,S)-Palonosetron Hydrochloride be shipped internationally?

Yes. (S,S)-Palonosetron Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.