Tacrolimus 19-epimer

Name: Tacrolimus 19-epimer
Brand: Vaqora Chemicals
SKU: VQ-028174

About Tacrolimus 19-epimer

Vaqora Chemicals supplies Tacrolimus 19-epimer, an impurity of Tacrolimus registered under CAS number 144490-63-1. Formula C44H69NO12, molecular weight 804.0 g/mol. Alternative names: Tacrolimus anhydrous 19-epimer and Tacrolimus compound II.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Tacrolimus impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	Tacrolimus 19-epimer
Catalogue No.	VQ-028174
CAS Number	144490-63-1
IUPAC name	(1S,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
Molecular formula	C₄₄H₆₉NO₁₂
Molecular weight	804 g/mol
Exact mass	803.482
Grade	Reference Standard
HSN code	38229090
InChIKey	QJJXYPPXXYFBGM-XTNLUGHASA-N
SMILES	C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](/C=C(/C1)\C)CC=C)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC
PubChem CID	13819073

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 12
TPSA	178 Å²

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P316, P318, P319, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tacrolimus 19-epimer?

The CAS Registry Number of Tacrolimus 19-epimer is 144490-63-1. It is also known as Tacrolimus anhydrous 19-epimer, Tacrolimus compound II.

What is the molecular formula and molecular weight of Tacrolimus 19-epimer?

Tacrolimus 19-epimer has the molecular formula C44H69NO12 and a molecular weight of 804 g/mol.

What is Tacrolimus 19-epimer used for?

Tacrolimus 19-epimer is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tacrolimus 19-epimer can I order?

We supply Tacrolimus 19-epimer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tacrolimus 19-epimer?

Yes. Every lot of Tacrolimus 19-epimer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tacrolimus 19-epimer be shipped internationally?

Yes. Tacrolimus 19-epimer is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.