Tacrolimus Methyl Acryl Aldehyde

Name: Tacrolimus Methyl Acryl Aldehyde
Brand: Vaqora Chemicals
SKU: VQ-028170

About Tacrolimus Methyl Acryl Aldehyde

Tacrolimus Methyl Acryl Aldehyde (CAS 109466-74-2) is an impurity of Tacrolimus offered by Vaqora Chemicals. The compound has the formula C11H18O3, corresponding to a molecular weight of 198.26 g/mol. The IUPAC name is (E)-3-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-methylprop-2-enal.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Tacrolimus to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Tacrolimus Methyl Acryl Aldehyde in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	Tacrolimus Methyl Acryl Aldehyde
Catalogue No.	VQ-028170
CAS Number	109466-74-2
IUPAC name	(E)-3-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-methylprop-2-enal
Molecular formula	C₁₁H₁₈O₃
Molecular weight	198.26 g/mol
Exact mass	198.1256
Grade	Reference Standard
HSN code	38229090
InChIKey	ZTXGCGOIEHBZMQ-OJHBQYHASA-N
SMILES	C/C(=C\[C@@H]1CC[C@H]([C@@H](C1)OC)O)/C=O
PubChem CID	13819084

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²
Synonyms	3-((1R,3R,4R)-4-Hydroxy-3-methoxycyclohexyl)-2-methylacrylaldehyde, (E)-, (2E)-3-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-methylprop-2-enal, 2-Propenal, 3-(4-hydroxy-3-methoxycyclohexyl)-2-methyl-, [1R-[1a(E),3a,4ss]]- (9CI), (E)-3-[(1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl]-2-methyl-prop-2-enal, [1R-[1a(E),3a,4b]]-3-(4-Hydroxy-3-methoxycyclohexyl)-2-methyl-2-propenal

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H330Fatal if inhaled

Precautionary statements: P260, P262, P264, P270, P271, P280, P284, P301 + P316, P302 + P352, P304 + P340, P316, P320, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tacrolimus Methyl Acryl Aldehyde?

The CAS Registry Number of Tacrolimus Methyl Acryl Aldehyde is 109466-74-2. It is also known as 3-((1R,3R,4R)-4-Hydroxy-3-methoxycyclohexyl)-2-methylacrylaldehyde, (E)-, (2E)-3-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-methylprop-2-enal, 2-Propenal, 3-(4-hydroxy-3-methoxycyclohexyl)-2-methyl-, [1R-[1a(E),3a,4ss]]- (9CI).

What is the molecular formula and molecular weight of Tacrolimus Methyl Acryl Aldehyde?

Tacrolimus Methyl Acryl Aldehyde has the molecular formula C11H18O3 and a molecular weight of 198.26 g/mol. Its IUPAC name is (E)-3-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-methylprop-2-enal.

What is Tacrolimus Methyl Acryl Aldehyde used for?

Tacrolimus Methyl Acryl Aldehyde is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tacrolimus Methyl Acryl Aldehyde can I order?

We supply Tacrolimus Methyl Acryl Aldehyde in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tacrolimus Methyl Acryl Aldehyde?

Yes. Every lot of Tacrolimus Methyl Acryl Aldehyde is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tacrolimus Methyl Acryl Aldehyde be shipped internationally?

Yes. Tacrolimus Methyl Acryl Aldehyde is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.