Tamoxifen EP Impurity F (Free Base)

Name: Tamoxifen EP Impurity F (Free Base)
Brand: Vaqora Chemicals
SKU: VQ-034901

About Tamoxifen EP Impurity F (Free Base)

Tamoxifen EP Impurity F (Free Base) is a pharmacopeial impurity of Tamoxifen carrying the CAS registry number 31750-48-8. Formula C25H27NO, molecular weight 357.5 g/mol. The IUPAC name is 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N-methylethanamine. It is also known as Tamoxifen citrate impurity F or Tamoxifen Citrate - Impurity F.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Tamoxifen to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Tamoxifen EP Impurity F (Free Base) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Tamoxifen

View every impurity, metabolite and intermediate we list for Tamoxifen.

Tamoxifen impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tamoxifen EP Impurity F (Free Base)
Catalogue No.	VQ-034901
CAS Number	31750-48-8
IUPAC name	2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N-methylethanamine
Molecular formula	C₂₅H₂₇NO
Molecular weight	357.5 g/mol
Exact mass	357.2093
Grade	Reference Standard
HSN code	38229090
InChIKey	NYDCDZSEEAUOHN-IZHYLOQSSA-N
SMILES	CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCNC)/C3=CC=CC=C3
PubChem CID	6378383

Physical properties
Physical form	Solid
LogP (XLogP3)	6.7
H-bond donors / acceptors	1 / 2
TPSA	21.3 Å²
Synonyms	Tamoxifen citrate impurity F, Tamoxifen Citrate - Impurity F, N-Desmethyltamoxifen, Desmethyltamoxifen, n-, ICI 55,548, cis-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine, (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)(methyl)amine, (2-(4-((1Z)-1,2-diphenylbut-1-en-1-yl)phenoxy)ethyl)(methyl)amine, 2-(4-((1Z)-1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethanamine, N-demethyltamoxifen, N-desmethyl tamoxifen, (Z)-2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)-N-methylethanamine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H350May cause cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tamoxifen EP Impurity F (Free Base)?

The CAS Registry Number of Tamoxifen EP Impurity F (Free Base) is 31750-48-8. It is also known as Tamoxifen citrate impurity F, Tamoxifen Citrate - Impurity F, N-Desmethyltamoxifen.

What is the molecular formula and molecular weight of Tamoxifen EP Impurity F (Free Base)?

Tamoxifen EP Impurity F (Free Base) has the molecular formula C25H27NO and a molecular weight of 357.5 g/mol. Its IUPAC name is 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N-methylethanamine.

What is Tamoxifen EP Impurity F (Free Base) used for?

Tamoxifen EP Impurity F (Free Base) is supplied as a characterised reference material related to Tamoxifen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tamoxifen EP Impurity F (Free Base) can I order?

We supply Tamoxifen EP Impurity F (Free Base) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tamoxifen EP Impurity F (Free Base)?

Yes. Every lot of Tamoxifen EP Impurity F (Free Base) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tamoxifen EP Impurity F (Free Base) be shipped internationally?

Yes. Tamoxifen EP Impurity F (Free Base) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.