Teriflunomide-d4

Name: Teriflunomide-d4
Brand: Vaqora Chemicals
SKU: VQ-031468

About Teriflunomide-d4

Teriflunomide-d4 (CAS 1185240-22-5) is a stable isotope labelled analogue related to Teriflunomide offered by Vaqora Chemicals. The compound has the formula C12H9F3N2O2, corresponding to a molecular weight of 274.23 g/mol. The IUPAC name is (Z)-2-cyano-3-hydroxy-N-[2,3,5,6-tetradeuterio-4-(trifluoromethyl)phenyl]but-2-enamide. Common synonyms include TMIJ-0227.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Teriflunomide-d4 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Teriflunomide

View every impurity, metabolite and intermediate we list for Teriflunomide.

Teriflunomide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Teriflunomide-d4
Catalogue No.	VQ-031468
CAS Number	1185240-22-5
IUPAC name	(Z)-2-cyano-3-hydroxy-N-[2,3,5,6-tetradeuterio-4-(trifluoromethyl)phenyl]but-2-enamide
Molecular formula	C₁₂H₉F₃N₂O₂
Molecular weight	274.23 g/mol
Exact mass	274.0867
Grade	Reference Standard
HSN code	38229090
InChIKey	UTNUDOFZCWSZMS-KXFGXCNQSA-N
SMILES	[2H]C1=C(C(=C(C(=C1C(F)(F)F)[2H])[2H])NC(=O)/C(=C(/C)\O)/C#N)[2H]
PubChem CID	71313485

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	2 / 6
TPSA	73.1 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Teriflunomide-d4?

The CAS Registry Number of Teriflunomide-d4 is 1185240-22-5. It is also known as 2-cyano 3-hydroxy-N-(4-(trifluoromethyl) phenyl)-(2Z)-2-butenamide-D4, 2-cyano 3-hydroxy-N-[4-(trifluoromethyl) phenyl]-(2Z)-2-butenamide-D4, TMIJ-0227.

What is the molecular formula and molecular weight of Teriflunomide-d4?

Teriflunomide-d4 has the molecular formula C12H9F3N2O2 and a molecular weight of 274.23 g/mol. Its IUPAC name is (Z)-2-cyano-3-hydroxy-N-[2,3,5,6-tetradeuterio-4-(trifluoromethyl)phenyl]but-2-enamide.

What is Teriflunomide-d4 used for?

Teriflunomide-d4 is supplied as a characterised reference material related to Teriflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Teriflunomide-d4 can I order?

We supply Teriflunomide-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Teriflunomide-d4?

Yes. Every lot of Teriflunomide-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Teriflunomide-d4 be shipped internationally?

Yes. Teriflunomide-d4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.