Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phen… 165727-45-7

Name: Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate
Brand: Vaqora Chemicals
SKU: VQ-039388

About Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate

Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate is a metabolite or degradation product of Darunavir carrying the CAS registry number 165727-45-7. Formula C15H22ClNO3, molecular weight 299.79 g/mol. Its systematic (IUPAC) name is tert-butyl N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]carbamate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Darunavir, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Darunavir

View every impurity, metabolite and intermediate we list for Darunavir.

Darunavir impurities

Specifications & identifiers

Chemical identifiers
Product name	Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate
Catalogue No.	VQ-039388
CAS Number	165727-45-7
IUPAC name	tert-butyl N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]carbamate
Molecular formula	C₁₅H₂₂ClNO₃
Molecular weight	299.79 g/mol
Exact mass	299.1288
Grade	Reference Standard
HSN code	38229090
InChIKey	GFGQSTIUFXHAJS-QWHCGFSZSA-N
SMILES	CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)[C@@H](CCl)O
PubChem CID	7146645

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 3
TPSA	58.6 Å²
Synonyms	(1S,2S)-(1-Benzyl-3-chloro-2-hydroxypropyl)carbamic acid tert-butyl ester, 1,1-Dimethylethyl N-((1S,2S)-3-chloro-2-hydroxy-1-(phenylmethyl)propyl)carbamate, (1s,2s)-[3-chloro-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid 1,1-dimethylethyl ester, (1s, 2s)-(1-benzyl-3-chloro-2-hydroxy-propyl)-carbamic acid tert-butyl ester, (1S,2S)-[3-Chloro-2-hydroxy-1-(phenylmethyl)-propyl]carbamic acid, 1,1-dimethylethyl ether, (2S,3S)-(-)-3-tert-Butoxycarbonylamino-1-chloro-2-hydroxy-4-phenylbutane, (2S,3S)-N-tert-Butoxycarbonyl-3-amino-1-chloro-2-hydroxy-4-phenylbutane, (1S,2S)-[3-Chloro-2-hydroxy-1-(phenylmethyl)-propyl]carbamic acid-1,1-dimethylethyl ether, (1S,2S)-(1-Benzyl-3-chloro-2-hydroxy-propyl)-carbamic acid tert-butyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate?

The CAS Registry Number of Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate is 165727-45-7. It is also known as (1S,2S)-(1-Benzyl-3-chloro-2-hydroxypropyl)carbamic acid tert-butyl ester, 1,1-Dimethylethyl N-((1S,2S)-3-chloro-2-hydroxy-1-(phenylmethyl)propyl)carbamate, (1s,2s)-[3-chloro-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid 1,1-dimethylethyl ester.

What is the molecular formula and molecular weight of Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate?

Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate has the molecular formula C15H22ClNO3 and a molecular weight of 299.79 g/mol. Its IUPAC name is tert-butyl N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]carbamate.

What is Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate used for?

Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate is supplied as a characterised reference material related to Darunavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate can I order?

We supply Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate?

Yes. Every lot of Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate be shipped internationally?

Yes. We export Tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.