Thiamine EP Impurity D

Name: Thiamine EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-034190

About Thiamine EP Impurity D

Listed under CAS 490-82-4, Thiamine EP Impurity D is a pharmacopeial impurity of Thiamine available from Vaqora Chemicals. Its molecular formula is C12H16N4O2S and its molecular weight is 280.35 g/mol. Its systematic (IUPAC) name is 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one. It is also known as Oxo Thiamine or Thiamine - Impurity D.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Thiamine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Thiamine EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Thiamine

View every impurity, metabolite and intermediate we list for Thiamine.

Thiamine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Thiamine EP Impurity D
Catalogue No.	VQ-034190
CAS Number	490-82-4
IUPAC name	3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one
Molecular formula	C₁₂H₁₆N₄O₂S
Molecular weight	280.35 g/mol
Exact mass	280.0994
Grade	Reference Standard
HSN code	38229090
InChIKey	VXCONGLPCAPYEU-UHFFFAOYSA-N
SMILES	CC1=C(SC(=O)N1CC2=CN=C(N=C2N)C)CCO
PubChem CID	120267

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	2 / 6
TPSA	118 Å²
Synonyms	Oxo Thiamine, Thiamine - Impurity D, Thiamine thiazolone, 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-(3H)-thiazolone, 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolin-2-one, 4-Thiazolin-2-one, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-2(3H)-thiazolone, 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-2(3H)-thiazolone, 3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-2(3H)-one, Thiaminthiazolone, Thiamin Thiazolone, Tiamintiazolone

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thiamine EP Impurity D?

The CAS Registry Number of Thiamine EP Impurity D is 490-82-4. It is also known as Oxo Thiamine, Thiamine - Impurity D, Thiamine thiazolone.

What is the molecular formula and molecular weight of Thiamine EP Impurity D?

Thiamine EP Impurity D has the molecular formula C12H16N4O2S and a molecular weight of 280.35 g/mol. Its IUPAC name is 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-2-one.

What is Thiamine EP Impurity D used for?

Thiamine EP Impurity D is supplied as a characterised reference material related to Thiamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thiamine EP Impurity D can I order?

We supply Thiamine EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thiamine EP Impurity D?

Yes. Every lot of Thiamine EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thiamine EP Impurity D be shipped internationally?

Yes. We export Thiamine EP Impurity D worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.