Thiamine Pyrophosphate Chloride

Name: Thiamine Pyrophosphate Chloride
Brand: Vaqora Chemicals
SKU: VQ-028329

About Thiamine Pyrophosphate Chloride

Vaqora Chemicals supplies Thiamine Pyrophosphate Chloride, an impurity of Thiamine registered under CAS number 154-87-0. Its molecular formula is C12H19ClN4O7P2S and its molecular weight is 460.77 g/mol. Alternative names: Thiamine Pyrophosphate and Vitamin B1 pyrophosphate chloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Thiamine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Thiamine Pyrophosphate Chloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Thiamine

View every impurity, metabolite and intermediate we list for Thiamine.

Thiamine impurities

Specifications & identifiers

Chemical identifiers
Product name	Thiamine Pyrophosphate Chloride
Catalogue No.	VQ-028329
CAS Number	154-87-0
IUPAC name	2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate chloride
Molecular formula	C₁₂H₁₉ClN₄O₇P₂S
Molecular weight	460.77 g/mol
Exact mass	460.0138
Grade	Reference Standard
HSN code	38229090
InChIKey	YXVCLPJQTZXJLH-UHFFFAOYSA-N
SMILES	CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)O.[Cl-]
PubChem CID	9068

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 12
TPSA	197 Å²
Synonyms	Thiamine Pyrophosphate, Vitamin B1 pyrophosphate chloride, Thiaminediphosphate, B-Carbossilasi, thiamine diphosphate, Cocarboxylase chloride, thiamine diphosphate chloride, thiamine pyrophosphate hydrochloride, thiamine(1+) diphosphate chloride, Coenbione, Diphosphothiamin, Diphosphothiamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements: P261, P272, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 154-87-0

Cocarboxylase

CAS: 154-87-0
Formula: C₁₂H₁₉ClN₄O₇P₂S
MW: 460.77 g/mol

VQ-020498

Frequently asked questions

What is the CAS number of Thiamine Pyrophosphate Chloride?

The CAS Registry Number of Thiamine Pyrophosphate Chloride is 154-87-0. It is also known as Thiamine Pyrophosphate, Vitamin B1 pyrophosphate chloride, Thiaminediphosphate.

What is the molecular formula and molecular weight of Thiamine Pyrophosphate Chloride?

Thiamine Pyrophosphate Chloride has the molecular formula C12H19ClN4O7P2S and a molecular weight of 460.77 g/mol. Its IUPAC name is 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate chloride.

What is Thiamine Pyrophosphate Chloride used for?

Thiamine Pyrophosphate Chloride is supplied as a characterised reference material related to Thiamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thiamine Pyrophosphate Chloride can I order?

We supply Thiamine Pyrophosphate Chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thiamine Pyrophosphate Chloride?

Yes. Every lot of Thiamine Pyrophosphate Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thiamine Pyrophosphate Chloride be shipped internationally?

Yes. Thiamine Pyrophosphate Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.