Thiamine EP Impurity A

Name: Thiamine EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-028326

About Thiamine EP Impurity A

Thiamine EP Impurity A is a pharmacopeial impurity of Thiamine carrying the CAS registry number 2380-61-2. The compound has the formula C12H16N4O4S2, corresponding to a molecular weight of 344.4 g/mol. Systematically, it is named 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl sulfate. It is also known as Thiamine Sulfate or Thiamine - Impurity A.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Thiamine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Thiamine EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Thiamine

View every impurity, metabolite and intermediate we list for Thiamine.

Thiamine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Thiamine EP Impurity A
Catalogue No.	VQ-028326
CAS Number	2380-61-2
IUPAC name	2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl sulfate
Molecular formula	C₁₂H₁₆N₄O₄S₂
Molecular weight	344.4 g/mol
Exact mass	344.0613
Grade	Reference Standard
HSN code	38229090
InChIKey	DXANYXRZRNXGSC-UHFFFAOYSA-N
SMILES	CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOS(=O)(=O)[O-]
PubChem CID	71468986

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	1 / 8
TPSA	159 Å²
Synonyms	Thiamine Sulfate, Thiamine - Impurity A, Thiamine hydrochloride impurity A, 2-(3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-4-methylthiazol-3-ium-5-yl)ethyl sulfate, Thiamine Impurity A HCl, Thiamine sulfate inner salt, Thiamine hydrogen sulfate ester, 2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-thiazol-3-ium-5-yl]ethyl sulfate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements: P261, P272, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thiamine EP Impurity A?

The CAS Registry Number of Thiamine EP Impurity A is 2380-61-2. It is also known as Thiamine Sulfate, Thiamine - Impurity A, Thiamine hydrochloride impurity A.

What is the molecular formula and molecular weight of Thiamine EP Impurity A?

Thiamine EP Impurity A has the molecular formula C12H16N4O4S2 and a molecular weight of 344.4 g/mol. Its IUPAC name is 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl sulfate.

What is Thiamine EP Impurity A used for?

Thiamine EP Impurity A is supplied as a characterised reference material related to Thiamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thiamine EP Impurity A can I order?

We supply Thiamine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thiamine EP Impurity A?

Yes. Every lot of Thiamine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thiamine EP Impurity A be shipped internationally?

Yes. Thiamine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.