Tofacitinib N-hydroxy impurity

Name: Tofacitinib N-hydroxy impurity
Brand: Vaqora Chemicals
SKU: VQ-043333

About Tofacitinib N-hydroxy impurity

Tofacitinib N-hydroxy impurity (CAS 2459302-76-0) is an impurity of Tofacitinib offered by Vaqora Chemicals. Its molecular formula is C13H19N5O and its molecular weight is 261.32 g/mol. Its systematic (IUPAC) name is N-[(3R,4R)-1-hydroxy-4-methylpiperidin-3-yl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Tofacitinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Tofacitinib N-hydroxy impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tofacitinib

View every impurity, metabolite and intermediate we list for Tofacitinib.

Tofacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Tofacitinib N-hydroxy impurity
Catalogue No.	VQ-043333
CAS Number	2459302-76-0
IUPAC name	N-[(3R,4R)-1-hydroxy-4-methylpiperidin-3-yl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Molecular formula	C₁₃H₁₉N₅O
Molecular weight	261.32 g/mol
Exact mass	261.159
Grade	Reference Standard
HSN code	38229090
InChIKey	GZVGGNOCKBKBJH-KOLCDFICSA-N
SMILES	C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)O
PubChem CID	150381453

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	2 / 5
TPSA	68.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tofacitinib N-hydroxy impurity?

The CAS Registry Number of Tofacitinib N-hydroxy impurity is 2459302-76-0. It is also known as (3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-ol.

What is the molecular formula and molecular weight of Tofacitinib N-hydroxy impurity?

Tofacitinib N-hydroxy impurity has the molecular formula C13H19N5O and a molecular weight of 261.32 g/mol. Its IUPAC name is N-[(3R,4R)-1-hydroxy-4-methylpiperidin-3-yl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine.

What is Tofacitinib N-hydroxy impurity used for?

Tofacitinib N-hydroxy impurity is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tofacitinib N-hydroxy impurity can I order?

We supply Tofacitinib N-hydroxy impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tofacitinib N-hydroxy impurity?

Yes. Every lot of Tofacitinib N-hydroxy impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tofacitinib N-hydroxy impurity be shipped internationally?

Yes. We export Tofacitinib N-hydroxy impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.