Tolcapone 3-Beta-D-Glucuronide

Name: Tolcapone 3-Beta-D-Glucuronide
Brand: Vaqora Chemicals
SKU: VQ-045252

About Tolcapone 3-Beta-D-Glucuronide

Vaqora Chemicals supplies Tolcapone 3-Beta-D-Glucuronide, a metabolite or degradation product of Tolcapone registered under CAS number 204853-33-8. Formula C20H19NO11, molecular weight 449.4 g/mol. Its systematic (IUPAC) name is (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-hydroxy-5-(4-methylbenzoyl)-3-nitrophenoxy]oxane-2-carboxylic acid. Common synonyms include Tolcapone O-beta-D-glucuronide and Tolcapone 3-|A-D-Glucuronide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Tolcapone, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Tolcapone 3-Beta-D-Glucuronide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tolcapone

View every impurity, metabolite and intermediate we list for Tolcapone.

Tolcapone impurities

Specifications & identifiers

Chemical identifiers
Product name	Tolcapone 3-Beta-D-Glucuronide
Catalogue No.	VQ-045252
CAS Number	204853-33-8
IUPAC name	(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-hydroxy-5-(4-methylbenzoyl)-3-nitrophenoxy]oxane-2-carboxylic acid
Molecular formula	C₂₀H₁₉NO₁₁
Molecular weight	449.4 g/mol
Exact mass	449.0958
Grade	Reference Standard
HSN code	38229090
InChIKey	QQQCXCUCFPMHBX-HBWRTXEVSA-N
SMILES	CC1=CC=C(C=C1)C(=O)C2=CC(=C(C(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O)O)[N+](=O)[O-]
PubChem CID	29987498

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	5 / 11
TPSA	200 Å²
Synonyms	Tolcapone O-beta-D-glucuronide, Tolcapone 3-, A-D-Glucuronide, beta-D-Glucopyranosiduronic acid, 2-hydroxy-5-(4-methylbenzoyl)-3-nitrophenyl, Tolcapone 3--D-Glucuronide, Tolcapone 3-O-beta-D-glucuronide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tolcapone 3-Beta-D-Glucuronide?

The CAS Registry Number of Tolcapone 3-Beta-D-Glucuronide is 204853-33-8. It is also known as Tolcapone O-beta-D-glucuronide, Tolcapone 3-, A-D-Glucuronide.

What is the molecular formula and molecular weight of Tolcapone 3-Beta-D-Glucuronide?

Tolcapone 3-Beta-D-Glucuronide has the molecular formula C20H19NO11 and a molecular weight of 449.4 g/mol. Its IUPAC name is (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-hydroxy-5-(4-methylbenzoyl)-3-nitrophenoxy]oxane-2-carboxylic acid.

What is Tolcapone 3-Beta-D-Glucuronide used for?

Tolcapone 3-Beta-D-Glucuronide is supplied as a characterised reference material related to Tolcapone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tolcapone 3-Beta-D-Glucuronide can I order?

We supply Tolcapone 3-Beta-D-Glucuronide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tolcapone 3-Beta-D-Glucuronide?

Yes. Every lot of Tolcapone 3-Beta-D-Glucuronide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tolcapone 3-Beta-D-Glucuronide be shipped internationally?

Yes. We export Tolcapone 3-Beta-D-Glucuronide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.