Tolvaptan

Name: Tolvaptan
Brand: Vaqora Chemicals
SKU: VQ-028449

About Tolvaptan

Listed under CAS 150683-30-0, Tolvaptan is a high-purity reference standard of Tolvaptan available from Vaqora Chemicals. Its molecular formula is C26H25ClN2O3 and its molecular weight is 448.9 g/mol. Systematically, it is named N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide. Alternative names: (R)-(+)-Tolvaptan and (S)-(-)-Tolvaptan.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Tolvaptan, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Tolvaptan in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tolvaptan

View every impurity, metabolite and intermediate we list for Tolvaptan.

Tolvaptan impurities

Specifications & identifiers

Chemical identifiers
Product name	Tolvaptan
Catalogue No.	VQ-028449
CAS Number	150683-30-0
IUPAC name	N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
Molecular formula	C₂₆H₂₅ClN₂O₃
Molecular weight	448.9 g/mol
Exact mass	448.1554
Grade	Reference Standard
HSN code	38229090
InChIKey	GYHCTFXIZSNGJT-UHFFFAOYSA-N
SMILES	CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C
PubChem CID	216237

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	2 / 3
TPSA	69.6 Å²
Synonyms	(R)-(+)-Tolvaptan, (S)-(-)-Tolvaptan, benzazepine derivative, 32, Tolvaptan (OPC-41061), Tolvaptan - Bio-X trade mark

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P263, P264, P270, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tolvaptan?

The CAS Registry Number of Tolvaptan is 150683-30-0. It is also known as (R)-(+)-Tolvaptan, (S)-(-)-Tolvaptan, benzazepine derivative, 32.

What is the molecular formula and molecular weight of Tolvaptan?

Tolvaptan has the molecular formula C26H25ClN2O3 and a molecular weight of 448.9 g/mol. Its IUPAC name is N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide.

What is Tolvaptan used for?

Tolvaptan is supplied as a characterised reference material related to Tolvaptan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tolvaptan can I order?

We supply Tolvaptan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tolvaptan?

Yes. Every lot of Tolvaptan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tolvaptan be shipped internationally?

Yes. Tolvaptan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.