Topiramate-d12

Name: Topiramate-d12
Brand: Vaqora Chemicals
SKU: VQ-042611

About Topiramate-d12

Topiramate-d12 (CAS 1279037-95-4) is a stable isotope labelled analogue related to Topiramate offered by Vaqora Chemicals. The compound has the formula C12H21NO8S, corresponding to a molecular weight of 351.44 g/mol. Alternative names: Topiramate-d12 (di-iso-propylidene-d12) and Topiramate-D12 (major).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Topiramate-d12 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Topiramate

View every impurity, metabolite and intermediate we list for Topiramate.

Topiramate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Topiramate-d12
Catalogue No.	VQ-042611
CAS Number	1279037-95-4
IUPAC name	[(1R,2S,6S,9R)-4,4,11,11-tetrakis(trideuteriomethyl)-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methyl sulfamate
Molecular formula	C₁₂H₂₁NO₈S
Molecular weight	351.44 g/mol
Exact mass	351.1741
Grade	Reference Standard
HSN code	38229090
InChIKey	KJADKKWYZYXHBB-RFYKXYJISA-N
SMILES	[2H]C([2H])([2H])C1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C([2H])([2H])[2H])C([2H])([2H])[2H])COS(=O)(=O)N)C([2H])([2H])[2H]
PubChem CID	45040550

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.8
H-bond donors / acceptors	1 / 9
TPSA	124 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Topiramate-d12?

The CAS Registry Number of Topiramate-d12 is 1279037-95-4. It is also known as Topiramate-d12 (di-iso-propylidene-d12), Topiramate-D12 (major).

What is the molecular formula and molecular weight of Topiramate-d12?

Topiramate-d12 has the molecular formula C12H21NO8S and a molecular weight of 351.44 g/mol. Its IUPAC name is [(1R,2S,6S,9R)-4,4,11,11-tetrakis(trideuteriomethyl)-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methyl sulfamate.

What is Topiramate-d12 used for?

Topiramate-d12 is supplied as a characterised reference material related to Topiramate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Topiramate-d12 can I order?

We supply Topiramate-d12 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Topiramate-d12?

Yes. Every lot of Topiramate-d12 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Topiramate-d12 be shipped internationally?

Yes. Topiramate-d12 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.