Tovorafenib

Name: Tovorafenib
Brand: Vaqora Chemicals
SKU: VQ-007810

About Tovorafenib

Listed under CAS 1096708-71-2, Tovorafenib is a high-purity reference standard of Tovorafenib available from Vaqora Chemicals. Its molecular formula is C17H12Cl2F3N7O2S and its molecular weight is 506.3 g/mol. Common synonyms include Tak-580 and BIIB-024.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a reference sample of Tovorafenib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Tovorafenib is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tovorafenib

View every impurity, metabolite and intermediate we list for Tovorafenib.

Tovorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Tovorafenib
Catalogue No.	VQ-007810
CAS Number	1096708-71-2
IUPAC name	2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide
Molecular formula	C₁₇H₁₂Cl₂F₃N₇O₂S
Molecular weight	506.3 g/mol
Exact mass	505.0102
Grade	Reference Standard
HSN code	38229090
InChIKey	VWMJHAFYPMOMGF-ZCFIWIBFSA-N
SMILES	C[C@H](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl
PubChem CID	25161177

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	3 / 11
TPSA	164 Å²
Synonyms	Tak-580, BIIB-024, MLN-2480, BIIB 024, DAY-101, Tak 580, DAY 101, pan-RAF Kinase Inhibitor DAY101, MLN 2480, C17H12Cl2F3N7O2S, Ojemda (TN), Tovorafenib (JAN/USAN/INN)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tovorafenib?

The CAS Registry Number of Tovorafenib is 1096708-71-2. It is also known as Tak-580, BIIB-024, MLN-2480.

What is the molecular formula and molecular weight of Tovorafenib?

Tovorafenib has the molecular formula C17H12Cl2F3N7O2S and a molecular weight of 506.3 g/mol. Its IUPAC name is 2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide.

What is Tovorafenib used for?

Tovorafenib is supplied as a characterised reference material related to Tovorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tovorafenib can I order?

We supply Tovorafenib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tovorafenib?

Yes. Every lot of Tovorafenib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tovorafenib be shipped internationally?

Yes. We export Tovorafenib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.