Tucatinib

Name: Tucatinib
Brand: Vaqora Chemicals
SKU: VQ-007825

About Tucatinib

Vaqora Chemicals supplies Tucatinib, a high-purity reference standard of Tucatinib registered under CAS number 937263-43-9. With the molecular formula C26H24N8O2, it has a molar mass of 480.5 g/mol. Alternative names: ONT-380 and Irbinitinib. ARRY-380. ONT-380.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this Tucatinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tucatinib

View every impurity, metabolite and intermediate we list for Tucatinib.

Tucatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Tucatinib
Catalogue No.	VQ-007825
CAS Number	937263-43-9
IUPAC name	6-N-(4,4-dimethyl-5H-1,3-oxazol-2-yl)-4-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazoline-4,6-diamine
Molecular formula	C₂₆H₂₄N₈O₂
Molecular weight	480.5 g/mol
Exact mass	480.2022
Grade	Reference Standard
HSN code	38229090
InChIKey	SDEAXTCZPQIFQM-UHFFFAOYSA-N
SMILES	CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5
PubChem CID	51039094

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	2 / 8
TPSA	111 Å²
Synonyms	ONT-380, Irbinitinib, ARRY-380, Tukysa (TN), Example 11 (WO2007059257A2), Example 11 [WO2007059257A2], Arry 380, ONT 380, Tucatinib, Tucatinib (USAN/INN), Irbinitinib(ARRY-380)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tucatinib?

The CAS Registry Number of Tucatinib is 937263-43-9. It is also known as ONT-380, Irbinitinib, ARRY-380.

What is the molecular formula and molecular weight of Tucatinib?

Tucatinib has the molecular formula C26H24N8O2 and a molecular weight of 480.5 g/mol. Its IUPAC name is 6-N-(4,4-dimethyl-5H-1,3-oxazol-2-yl)-4-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazoline-4,6-diamine.

What is Tucatinib used for?

Tucatinib is supplied as a characterised reference material related to Tucatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tucatinib can I order?

We supply Tucatinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tucatinib?

Yes. Every lot of Tucatinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tucatinib be shipped internationally?

Yes. We export Tucatinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.