Valsartan Impurity 8 (Freebase)

Name: Valsartan Impurity 8 (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-006098

About Valsartan Impurity 8 (Freebase)

Vaqora Chemicals supplies Valsartan Impurity 8 (Freebase), an impurity of Valsartan registered under CAS number 137863-89-9. With the molecular formula C20H22N2O2, it has a molar mass of 322.4 g/mol. The IUPAC name is methyl (2S)-2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-methylbutanoate. It is also known as Valsartan impurity D (USP-MC).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Valsartan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Valsartan Impurity 8 (Freebase)
Catalogue No.	VQ-006098
CAS Number	137863-89-9
IUPAC name	methyl (2S)-2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-methylbutanoate
Molecular formula	C₂₀H₂₂N₂O₂
Molecular weight	322.4 g/mol
Exact mass	322.1681
Grade	Reference Standard
HSN code	38229090
InChIKey	ZQHINOUCNQKQEV-IBGZPJMESA-N
SMILES	CC(C)[C@@H](C(=O)OC)NCC1=CC=C(C=C1)C2=CC=CC=C2C#N
PubChem CID	16744794

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	1 / 4
TPSA	62.1 Å²
Synonyms	(S)-Methyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoate, N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester, Methyl ((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valinate, N-((2'-Cyano(1,1'-biphenyl)-4-yl)methyl)-L-valine methyl ester, N-[(2'-Cyano-(1,1'-biphenyl)-4-yl)methyl)]valine methyl ester, L-Valine, N-((2'-cyano(1,1'-biphenyl)-4-yl)methyl)-, methyl ester, Valsartan impurity D (USP-MC), Methyl N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-L-valinate, L-Valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-, methyl ester, N-((2'-Cyano-(1,1'-biphenyl)-4-yl)methyl))valine methyl ester, N-(2'-Cyano-(1'1'-biphenyl)-4-yl)-methyl)-L-valine methyl ester, N-[2'-Cyano-[1'1'-biphenyl]-4-yl)-methyl]-L-valine methyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Valsartan Impurity 8 (Freebase)?

The CAS Registry Number of Valsartan Impurity 8 (Freebase) is 137863-89-9. It is also known as (S)-Methyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoate, N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester, Methyl ((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valinate.

What is the molecular formula and molecular weight of Valsartan Impurity 8 (Freebase)?

Valsartan Impurity 8 (Freebase) has the molecular formula C20H22N2O2 and a molecular weight of 322.4 g/mol. Its IUPAC name is methyl (2S)-2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-methylbutanoate.

What is Valsartan Impurity 8 (Freebase) used for?

Valsartan Impurity 8 (Freebase) is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Valsartan Impurity 8 (Freebase) can I order?

We supply Valsartan Impurity 8 (Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Valsartan Impurity 8 (Freebase)?

Yes. Every lot of Valsartan Impurity 8 (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Valsartan Impurity 8 (Freebase) be shipped internationally?

Yes. We export Valsartan Impurity 8 (Freebase) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.