N-Methyl-4-nitroaniline

Name: N-Methyl-4-nitroaniline
Brand: Vaqora Chemicals
SKU: VQ-032172

About N-Methyl-4-nitroaniline

Vaqora Chemicals supplies N-Methyl-4-nitroaniline, a process intermediate or related compound of Nintedanib registered under CAS number 100-15-2. The compound has the formula C7H8N2O2, corresponding to a molecular weight of 152.15 g/mol. Common synonyms include Benzenamine, N-methyl-4-nitro- and N-Methyl-p-nitroaniline.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Nintedanib, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Methyl-4-nitroaniline is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Methyl-4-nitroaniline
Catalogue No.	VQ-032172
CAS Number	100-15-2
IUPAC name	N-methyl-4-nitroaniline
Molecular formula	C₇H₈N₂O₂
Molecular weight	152.15 g/mol
Exact mass	152.0586
HSN code	2933
InChIKey	XIFJZJPMHNUGRA-UHFFFAOYSA-N
SMILES	CNC1=CC=C(C=C1)[N+](=O)[O-]
PubChem CID	7483

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 3
TPSA	57.9 Å²
Synonyms	Benzenamine, N-methyl-4-nitro-, N-Methyl-p-nitroaniline, 4-Nitro-N-methylaniline, N-Methyl-p-nitraniline, p-Nitro-N-methylaniline, p-(Methylamino)nitrobenzene, N-Monomethyl-p-nitroaniline, Aniline, N-methyl-p-nitro-, methyl(4-nitrophenyl)amine, 4-(Methylamino)nitrobenzene, N-methyl-para-nitroaniline

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H373May causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P260, P261, P262, P264, P270, P271, P273, P280, P301 + P316, P302 + P352, P304 + P340, P316, P319, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methyl-4-nitroaniline?

The CAS Registry Number of N-Methyl-4-nitroaniline is 100-15-2. It is also known as Benzenamine, N-methyl-4-nitro-, N-Methyl-p-nitroaniline, 4-Nitro-N-methylaniline.

What is the molecular formula and molecular weight of N-Methyl-4-nitroaniline?

N-Methyl-4-nitroaniline has the molecular formula C7H8N2O2 and a molecular weight of 152.15 g/mol. Its IUPAC name is N-methyl-4-nitroaniline.

What is N-Methyl-4-nitroaniline used for?

N-Methyl-4-nitroaniline is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Methyl-4-nitroaniline can I order?

We supply N-Methyl-4-nitroaniline, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methyl-4-nitroaniline?

Yes. Every lot of N-Methyl-4-nitroaniline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methyl-4-nitroaniline be shipped internationally?

Yes. N-Methyl-4-nitroaniline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.