N-Methyl-4-nitro-N-nitrosoaniline

Name: N-Methyl-4-nitro-N-nitrosoaniline
Brand: Vaqora Chemicals
SKU: VQ-028971

About N-Methyl-4-nitro-N-nitrosoaniline

Listed under CAS 943-41-9, N-Methyl-4-nitro-N-nitrosoaniline is a nitrosamine impurity of Nintedanib available from Vaqora Chemicals. With the molecular formula C7H7N3O3, it has a molar mass of 181.15 g/mol. Systematically, it is named N-methyl-N-(4-nitrophenyl)nitrous amide. Alternative names: N-Nitroso-N-methyl-4-nitroaniline and N-Methyl-4-nitro-N-nitrosobenzenamine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Methyl-4-nitro-N-nitrosoaniline is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Methyl-4-nitro-N-nitrosoaniline
Catalogue No.	VQ-028971
CAS Number	943-41-9
IUPAC name	N-methyl-N-(4-nitrophenyl)nitrous amide
Molecular formula	C₇H₇N₃O₃
Molecular weight	181.15 g/mol
Exact mass	181.0487
Grade	Reference Standard
HSN code	38229090
InChIKey	AMTRFSFECFPSHF-UHFFFAOYSA-N
SMILES	CN(C1=CC=C(C=C1)[N+](=O)[O-])N=O
PubChem CID	13671

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	0 / 5
TPSA	78.5 Å²
Synonyms	N-Nitroso-N-methyl-4-nitroaniline, N-Methyl-4-nitro-N-nitrosobenzenamine, N-Methyl-p-nitro-N-nitrosoaniline, Benzenamine, N-methyl-4-nitro-N-nitroso-, ANILINE, N-METHYL-p-NITRO-N-NITROSO-, 4-nitro-N-nitroso-N-methyl-aniline, Benzenamine,n-methyl-4-nitro-n-nitroso-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methyl-4-nitro-N-nitrosoaniline?

The CAS Registry Number of N-Methyl-4-nitro-N-nitrosoaniline is 943-41-9. It is also known as N-Nitroso-N-methyl-4-nitroaniline, N-Methyl-4-nitro-N-nitrosobenzenamine, N-Methyl-p-nitro-N-nitrosoaniline.

What is the molecular formula and molecular weight of N-Methyl-4-nitro-N-nitrosoaniline?

N-Methyl-4-nitro-N-nitrosoaniline has the molecular formula C7H7N3O3 and a molecular weight of 181.15 g/mol. Its IUPAC name is N-methyl-N-(4-nitrophenyl)nitrous amide.

What is N-Methyl-4-nitro-N-nitrosoaniline used for?

N-Methyl-4-nitro-N-nitrosoaniline is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Methyl-4-nitro-N-nitrosoaniline can I order?

We supply N-Methyl-4-nitro-N-nitrosoaniline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methyl-4-nitro-N-nitrosoaniline?

Yes. Every lot of N-Methyl-4-nitro-N-nitrosoaniline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methyl-4-nitro-N-nitrosoaniline be shipped internationally?

Yes. We export N-Methyl-4-nitro-N-nitrosoaniline worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.