Cetirizine Impurity B (Dihydrochloride)

Name: Cetirizine Impurity B (Dihydrochloride)
Brand: Vaqora Chemicals
SKU: VQ-004629

About Cetirizine Impurity B (Dihydrochloride)

Vaqora Chemicals supplies Cetirizine Impurity B (Dihydrochloride), an impurity of Cetirizine registered under CAS number 1000690-91-4. With the molecular formula C19H23Cl3N2O2, it has a molar mass of 417.8 g/mol. Systematically, it is named 2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]acetic acid. Dihydrochloride. Alternative names: Cetirizine impurity B Dihydrochloride and Cetirizine EP impurity B.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Cetirizine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cetirizine Impurity B (Dihydrochloride) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cetirizine

View every impurity, metabolite and intermediate we list for Cetirizine.

Cetirizine impurities

Specifications & identifiers

Chemical identifiers
Product name	Cetirizine Impurity B (Dihydrochloride)
Catalogue No.	VQ-004629
CAS Number	1000690-91-4
IUPAC name	2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]acetic acid;dihydrochloride
Molecular formula	C₁₉H₂₃Cl₃N₂O₂
Molecular weight	417.8 g/mol
Exact mass	416.0825
Grade	Reference Standard
HSN code	38229090
InChIKey	LSPZEDLYSAUAQV-UHFFFAOYSA-N
SMILES	C1CN(CCN1CC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
PubChem CID	68928581

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 4
TPSA	43.8 Å²
Synonyms	De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineacetic Acid Dihydrochloride, Cetirizine impurity B Dihydrochloride, 4-((4-Chlorophenyl)phenylmethyl)-1-piperazineacetic Acid Dihydrochloride, 2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid dihydrochloride, (RS)-2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]acetic Acid Dihydrochloride, Cetirizine EP Impurity B, 4X-10832etirizine Impurity 20, USP Cetirizine Acetic Acid 2Hcl, 1-Piperazineacetic acid, 4-[(4-chlorophenyl)phenylmethyl]-, hydrochloride (1:2), 2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid dihydrochloride salt

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cetirizine Impurity B (Dihydrochloride)?

The CAS Registry Number of Cetirizine Impurity B (Dihydrochloride) is 1000690-91-4. It is also known as De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineacetic Acid Dihydrochloride, Cetirizine impurity B Dihydrochloride.

What is the molecular formula and molecular weight of Cetirizine Impurity B (Dihydrochloride)?

Cetirizine Impurity B (Dihydrochloride) has the molecular formula C19H23Cl3N2O2 and a molecular weight of 417.8 g/mol.

What is Cetirizine Impurity B (Dihydrochloride) used for?

Cetirizine Impurity B (Dihydrochloride) is supplied as a characterised reference material related to Cetirizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cetirizine Impurity B (Dihydrochloride) can I order?

We supply Cetirizine Impurity B (Dihydrochloride) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cetirizine Impurity B (Dihydrochloride)?

Yes. Every lot of Cetirizine Impurity B (Dihydrochloride) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cetirizine Impurity B (Dihydrochloride) be shipped internationally?

Yes. Cetirizine Impurity B (Dihydrochloride) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.