Losartan EP Impurity J

Name: Losartan EP Impurity J
Brand: Vaqora Chemicals
SKU: VQ-026517

About Losartan EP Impurity J

Listed under CAS 1006062-27-6, Losartan EP Impurity J is a pharmacopeial impurity of Losartan available from Vaqora Chemicals. The compound has the formula C24H25ClN6O2, corresponding to a molecular weight of 464.9 g/mol. Its systematic (IUPAC) name is [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methyl acetate. Common synonyms include Losartan Potassium EP Impurity J and Losartan Potassium - Impurity J.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Losartan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Losartan EP Impurity J is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Losartan

View every impurity, metabolite and intermediate we list for Losartan.

Losartan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Losartan EP Impurity J
Catalogue No.	VQ-026517
CAS Number	1006062-27-6
IUPAC name	[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methyl acetate
Molecular formula	C₂₄H₂₅ClN₆O₂
Molecular weight	464.9 g/mol
Exact mass	464.1728
Grade	Reference Standard
HSN code	38229090
InChIKey	HIUYRCVDCVFSBP-UHFFFAOYSA-N
SMILES	CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)COC(=O)C)Cl
PubChem CID	46780033

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	1 / 6
TPSA	98.6 Å²
Synonyms	Losartan Potassium EP Impurity J, Losartan Potassium - Impurity J, O-Acetyl Losartan, Losartan potassium specified impurity J, Losartan Impurity J, o-acethyllosartan

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Losartan EP Impurity J?

The CAS Registry Number of Losartan EP Impurity J is 1006062-27-6. It is also known as Losartan Potassium EP Impurity J, Losartan Potassium - Impurity J, O-Acetyl Losartan.

What is the molecular formula and molecular weight of Losartan EP Impurity J?

Losartan EP Impurity J has the molecular formula C24H25ClN6O2 and a molecular weight of 464.9 g/mol. Its IUPAC name is [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methyl acetate.

What is Losartan EP Impurity J used for?

Losartan EP Impurity J is supplied as a characterised reference material related to Losartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Losartan EP Impurity J can I order?

We supply Losartan EP Impurity J in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Losartan EP Impurity J?

Yes. Every lot of Losartan EP Impurity J is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Losartan EP Impurity J be shipped internationally?

Yes. Losartan EP Impurity J is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.