Sorafenib Hydroxydemethylamine

Name: Sorafenib Hydroxydemethylamine
Brand: Vaqora Chemicals
SKU: VQ-028089

About Sorafenib Hydroxydemethylamine

Listed under CAS 1012058-78-4, Sorafenib Hydroxydemethylamine is a metabolite or degradation product of Sorafenib available from Vaqora Chemicals. Its molecular formula is C20H13ClF3N3O4 and its molecular weight is 451.8 g/mol. Its systematic (IUPAC) name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]pyridine-2-carboxylic acid. It is also known as Sorafenib metabolite M6.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Sorafenib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sorafenib Hydroxydemethylamine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Sorafenib Hydroxydemethylamine
Catalogue No.	VQ-028089
CAS Number	1012058-78-4
IUPAC name	4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]pyridine-2-carboxylic acid
Molecular formula	C₂₀H₁₃ClF₃N₃O₄
Molecular weight	451.8 g/mol
Exact mass	451.0547
Grade	Reference Standard
HSN code	38229090
InChIKey	IPCWVRAYBZXUMM-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1NC(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F)OC3=CC(=NC=C3)C(=O)O
PubChem CID	59772925

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	3 / 8
TPSA	101 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sorafenib Hydroxydemethylamine?

The CAS Registry Number of Sorafenib Hydroxydemethylamine is 1012058-78-4. It is also known as 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinic acid, Sorafenib metabolite M6, 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido) phenoxy)picolinic acid.

What is the molecular formula and molecular weight of Sorafenib Hydroxydemethylamine?

Sorafenib Hydroxydemethylamine has the molecular formula C20H13ClF3N3O4 and a molecular weight of 451.8 g/mol. Its IUPAC name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]pyridine-2-carboxylic acid.

What is Sorafenib Hydroxydemethylamine used for?

Sorafenib Hydroxydemethylamine is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sorafenib Hydroxydemethylamine can I order?

We supply Sorafenib Hydroxydemethylamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sorafenib Hydroxydemethylamine?

Yes. Every lot of Sorafenib Hydroxydemethylamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sorafenib Hydroxydemethylamine be shipped internationally?

Yes. We export Sorafenib Hydroxydemethylamine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.