(αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amin… 1012341-56-8

About (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid

(αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid is an impurity of Sacubitril carrying the CAS registry number 1012341-56-8. Formula C23H29NO4, molecular weight 383.5 g/mol. The IUPAC name is (2R,4R)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pentanoic acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Sacubitril, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	(αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid
Catalogue No.	VQ-027957
CAS Number	1012341-56-8
IUPAC name	(2R,4R)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pentanoic acid
Molecular formula	C₂₃H₂₉NO₄
Molecular weight	383.5 g/mol
Exact mass	383.2097
Grade	Reference Standard
HSN code	38229090
InChIKey	YNELJETWNMPEEH-OXQOHEQNSA-N
SMILES	C[C@H](C[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)OC(C)(C)C)C(=O)O
PubChem CID	58027483

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	2 / 4
TPSA	75.6 Å²
Synonyms	(2R,4R)-5-([1,1-Biphenyl]-4-yl)-4-(tert-butoxycarbonyl)amino-2-methylpentanoic acid, (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid, (2R,4R)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid, (2R,4R)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid, (2R,4R)-4-(tert-butoxycarbonylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid, (2R,4R)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoicacid, 5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid, (2R,4R)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid?

The CAS Registry Number of (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid is 1012341-56-8. It is also known as (2R,4R)-5-([1,1-Biphenyl]-4-yl)-4-(tert-butoxycarbonyl)amino-2-methylpentanoic acid, (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid, (2R,4R)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid.

What is the molecular formula and molecular weight of (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid?

(αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid has the molecular formula C23H29NO4 and a molecular weight of 383.5 g/mol. Its IUPAC name is (2R,4R)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pentanoic acid.

What is (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid used for?

(αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid can I order?

We supply (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid?

Yes. Every lot of (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid be shipped internationally?

Yes. We export (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.