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(S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione

Synonyms: N-Benzyl-(3S)-hydroxysuccinimide · 2,5-Pyrrolidinedione, 3-hydroxy-1-(phenylmethyl)-, (3S)- · N-Benzyl-(S)-malimide · (R)-benzyl 3-fluoropyrrolidine-1-carboxylate

CAS No.101469-91-4
FormulaC11H11NO3
Mol. weight205.21
Catalogue No.VQ-026370
PurityReference Standard
HSN38229090

(S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione (CAS 101469-91-4) – Larotrectinib impurity standard. C11H11NO3, MW 205.21. Vaqora Chemicals: COA, global shipping.

Pack sizesPrice on quotation · bulk available
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25 mg
50 mg
100 mg
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16-section GHS SDS
Export to 120+ countries
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About (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione

Vaqora Chemicals supplies (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione, a metabolite or degradation product of Larotrectinib registered under CAS number 101469-91-4. Its molecular formula is C11H11NO3 and its molecular weight is 205.21 g/mol. Its systematic (IUPAC) name is (3S)-1-benzyl-3-hydroxypyrrolidine-2,5-dione. It is also known as N-Benzyl-(3S)-hydroxysuccinimide or N-Benzyl-(S)-malimide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Larotrectinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling
  • Fine chemical synthesis

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Related to Larotrectinib

View every impurity, metabolite and intermediate we list for Larotrectinib.

Larotrectinib impurities

Specifications & identifiers

Chemical identifiers
Product name(S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione
Catalogue No.VQ-026370
CAS Number101469-91-4
IUPAC name(3S)-1-benzyl-3-hydroxypyrrolidine-2,5-dione
Molecular formulaC11H11NO3
Molecular weight205.21 g/mol
Exact mass205.0739
GradeReference Standard
HSN code38229090
InChIKeyVCPKAWKGCQTPCR-VIFPVBQESA-N
SMILESC1[C@@H](C(=O)N(C1=O)CC2=CC=CC=C2)O
PubChem CID10954694
Physical properties
Physical formSolid
LogP (XLogP3)0.1
H-bond donors / acceptors1 / 3
TPSA57.6 Ų
SynonymsN-Benzyl-(3S)-hydroxysuccinimide, 2,5-Pyrrolidinedione, 3-hydroxy-1-(phenylmethyl)-, (3S)-, N-Benzyl-(S)-malimide, (R)-benzyl 3-fluoropyrrolidine-1-carboxylate, (S) N-benzyl-3-hydroxypyrrolidine-2,5-dione, (3S)-N-Benzyl-3-hydroxypyrrolidine-2,5-dione, (S)-1-benzyl-3-hydroxy-2,5-pyrrolidine dione, (S)-1-benzyl-3-hydroxy-2,5-pyrrolidinedione, (3S)-1-benzyl-3-hydroxy-pyrrolidine-2,5-dione

Documents

Frequently asked questions

What is the CAS number of (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione?

The CAS Registry Number of (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione is 101469-91-4. It is also known as N-Benzyl-(3S)-hydroxysuccinimide, 2,5-Pyrrolidinedione, 3-hydroxy-1-(phenylmethyl)-, (3S)-, N-Benzyl-(S)-malimide.

What is the molecular formula and molecular weight of (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione?

(S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione has the molecular formula C11H11NO3 and a molecular weight of 205.21 g/mol. Its IUPAC name is (3S)-1-benzyl-3-hydroxypyrrolidine-2,5-dione.

What is (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione used for?

(S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione is supplied as a characterised reference material related to Larotrectinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione can I order?

We supply (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione?

Yes. Every lot of (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione be shipped internationally?

Yes. We export (S)-1-Benzyl-3-hydroxypyrrolidine-2,5-dione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.

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Why buyers choose Vaqora

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  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
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  • Custom synthesis & sourcing
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