Clarithromycin EP Impurity D

Name: Clarithromycin EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-020697

About Clarithromycin EP Impurity D

Clarithromycin EP Impurity D (CAS 101666-68-6) is a pharmacopeial impurity of Clarithromycin offered by Vaqora Chemicals. With the molecular formula C37H67NO13, it has a molar mass of 733.9 g/mol. It is also known as N-Desmethyl Clarithromycin or Clarithromycin - Impurity D.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Clarithromycin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Clarithromycin EP Impurity D is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Clarithromycin

View every impurity, metabolite and intermediate we list for Clarithromycin.

Clarithromycin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Clarithromycin EP Impurity D
Catalogue No.	VQ-020697
CAS Number	101666-68-6
IUPAC name	(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-6-[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
Molecular formula	C₃₇H₆₇NO₁₃
Molecular weight	733.9 g/mol
Exact mass	733.4612
Grade	Reference Standard
HSN code	38229090
InChIKey	CIJTVUQEURKBDL-RWJQBGPGSA-N
SMILES	CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)NC)O)(C)OC)C)C)O)(C)O
PubChem CID	11072636

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	5 / 14
TPSA	192 Å²
Synonyms	N-Desmethyl Clarithromycin, Clarithromycin - Impurity D, N-Desmethylclarithromycin, 3''-N-Demethylclarithromycin, Erythromycin, N-demethyl-6-O-methyl-, Clarithromycin_N-demethyl, N'-demethyl clarithromycin

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clarithromycin EP Impurity D?

The CAS Registry Number of Clarithromycin EP Impurity D is 101666-68-6. It is also known as N-Desmethyl Clarithromycin, Clarithromycin - Impurity D, N-Desmethylclarithromycin.

What is the molecular formula and molecular weight of Clarithromycin EP Impurity D?

Clarithromycin EP Impurity D has the molecular formula C37H67NO13 and a molecular weight of 733.9 g/mol.

What is Clarithromycin EP Impurity D used for?

Clarithromycin EP Impurity D is supplied as a characterised reference material related to Clarithromycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clarithromycin EP Impurity D can I order?

We supply Clarithromycin EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clarithromycin EP Impurity D?

Yes. Every lot of Clarithromycin EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clarithromycin EP Impurity D be shipped internationally?

Yes. Clarithromycin EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.