Palonosetron USP Related Compound B

Name: Palonosetron USP Related Compound B
Brand: Vaqora Chemicals
SKU: VQ-006566

About Palonosetron USP Related Compound B

Listed under CAS 1021456-82-5, Palonosetron USP Related Compound B is a pharmacopeial impurity of Palonosetron available from Vaqora Chemicals. The compound has the formula C19H22N2O2, corresponding to a molecular weight of 310.4 g/mol. Its systematic (IUPAC) name is 2-[(3S)-1-oxido-1-azoniabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4H-benzo[de]isoquinolin-1-one. Common synonyms include Dehydro palonosetron N-oxide and Palonosetron-3-ene N-Oxide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Palonosetron impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Palonosetron USP Related Compound B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Palonosetron

View every impurity, metabolite and intermediate we list for Palonosetron.

Palonosetron impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Palonosetron USP Related Compound B
Catalogue No.	VQ-006566
CAS Number	1021456-82-5
IUPAC name	2-[(3S)-1-oxido-1-azoniabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4H-benzo[de]isoquinolin-1-one
Molecular formula	C₁₉H₂₂N₂O₂
Molecular weight	310.4 g/mol
Exact mass	310.1681
Grade	Reference Standard
HSN code	38229090
InChIKey	UJTMVWDDYCEVNT-WAPLAKNRSA-N
SMILES	C1CC2=C3C(=CN(C(=O)C3=CC=C2)[C@@H]4C[N+]5(CCC4CC5)[O-])C1
PubChem CID	59745891

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	0 / 2
TPSA	38.4 Å²
Synonyms	(S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine 1-oxide, Dehydro palonosetron N-oxide, (3S)-3-(1-Oxo-5,6-dihydro-1H-benzo(de)isoquinolin-2(4H)-yl)quinuclidine 1-oxide, Palonosetron-3-ene N-Oxide, Palonosetron Impurity 53, (1S,3S,4S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine 1-oxide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Palonosetron USP Related Compound B?

The CAS Registry Number of Palonosetron USP Related Compound B is 1021456-82-5. It is also known as (S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine 1-oxide, Dehydro palonosetron N-oxide, (3S)-3-(1-Oxo-5,6-dihydro-1H-benzo(de)isoquinolin-2(4H)-yl)quinuclidine 1-oxide.

What is the molecular formula and molecular weight of Palonosetron USP Related Compound B?

Palonosetron USP Related Compound B has the molecular formula C19H22N2O2 and a molecular weight of 310.4 g/mol. Its IUPAC name is 2-[(3S)-1-oxido-1-azoniabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4H-benzo[de]isoquinolin-1-one.

What is Palonosetron USP Related Compound B used for?

Palonosetron USP Related Compound B is supplied as a characterised reference material related to Palonosetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Palonosetron USP Related Compound B can I order?

We supply Palonosetron USP Related Compound B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Palonosetron USP Related Compound B?

Yes. Every lot of Palonosetron USP Related Compound B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Palonosetron USP Related Compound B be shipped internationally?

Yes. Palonosetron USP Related Compound B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.