Ibrutinib Boc Amine Impurity

Name: Ibrutinib Boc Amine Impurity
Brand: Vaqora Chemicals
SKU: VQ-005056

About Ibrutinib Boc Amine Impurity

Ibrutinib Boc Amine Impurity (CAS 1022150-11-3) is an impurity of Ibrutinib offered by Vaqora Chemicals at a purity of 99.22%. With the molecular formula C27H30N6O3, it has a molar mass of 486.6 g/mol. Its systematic (IUPAC) name is tert-butyl (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate. Common synonyms include Ibrutinib Boc-Amine Impurity and CS-M2599.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Ibrutinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Ibrutinib Boc Amine Impurity in 10 mg, 25 mg and 50 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ibrutinib Boc Amine Impurity
Catalogue No.	VQ-005056
CAS Number	1022150-11-3
IUPAC name	tert-butyl (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate
Molecular formula	C₂₇H₃₀N₆O₃
Molecular weight	486.6 g/mol
Exact mass	486.2379
Grade	Reference Standard
Purity / assay	99.22%
HSN code	38229090
InChIKey	NTSAEGNFPKKRLX-LJQANCHMSA-N
SMILES	CC(C)(C)OC(=O)N1CCC[C@H](C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
PubChem CID	59799012

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	1 / 7
TPSA	108 Å²
Synonyms	tert-Butyl-1-carboxyl Piperidine analog of Ibrutinib, N-Boc-Ibrutinib ( tert-Butyl-1-carboxyl Piperidine analog of Ibrutinib), Ibrutinib Boc-Amine Impurity, (R)-1-(1-Boc-3-piperidinyl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CS-M2599, pyrazolo[3,4-d]pyrimidin-1-yl]-, (R)-3-[4-Amino-3-(4-phenoxy-phenyl)-, (R)-tert-butyl 3-(4-amino-3-(4-phenoxyphenyl)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ibrutinib Boc Amine Impurity?

The CAS Registry Number of Ibrutinib Boc Amine Impurity is 1022150-11-3. It is also known as tert-Butyl-1-carboxyl Piperidine analog of Ibrutinib, N-Boc-Ibrutinib ( tert-Butyl-1-carboxyl Piperidine analog of Ibrutinib), Ibrutinib Boc-Amine Impurity.

What is the molecular formula and molecular weight of Ibrutinib Boc Amine Impurity?

Ibrutinib Boc Amine Impurity has the molecular formula C27H30N6O3 and a molecular weight of 486.6 g/mol. Its IUPAC name is tert-butyl (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate.

What is Ibrutinib Boc Amine Impurity used for?

Ibrutinib Boc Amine Impurity is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ibrutinib Boc Amine Impurity can I order?

We supply Ibrutinib Boc Amine Impurity in Reference Standard (99.22%) grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ibrutinib Boc Amine Impurity?

Yes. Every lot of Ibrutinib Boc Amine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ibrutinib Boc Amine Impurity be shipped internationally?

Yes. Ibrutinib Boc Amine Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.