Nilotinib KSM Nitrate Impurity

Name: Nilotinib KSM Nitrate Impurity
Brand: Vaqora Chemicals
SKU: VQ-005375

About Nilotinib KSM Nitrate Impurity

Listed under CAS 1025716-99-7, Nilotinib KSM Nitrate Impurity is an impurity of Nilotinib available from Vaqora Chemicals, specified at 95% purity. Formula C10H14N4O5, molecular weight 270.24 g/mol. The IUPAC name is methyl 3-(diaminomethylideneamino)-4-methylbenzoate. Nitric acid. Common synonyms include Methyl 3-guanidino-4-methylbenzoate Nitrate and Nilotinib Impurity 1.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Nilotinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nilotinib KSM Nitrate Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib KSM Nitrate Impurity
Catalogue No.	VQ-005375
CAS Number	1025716-99-7
Other CAS	1025716-98-6
IUPAC name	methyl 3-(diaminomethylideneamino)-4-methylbenzoate;nitric acid
Molecular formula	C₁₀H₁₄N₄O₅
Molecular weight	270.24 g/mol
Exact mass	270.0964
Grade	Reference Standard
Purity / assay	95%
HSN code	38229090
InChIKey	SFHRCNFZNRMPOT-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)OC)N=C(N)N.[N+](=O)(O)[O-]
PubChem CID	46863880

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 6
TPSA	157 Å²
Synonyms	3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid methyl ester nitrate, 4-methyl-3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid methyl ester nitrate, Methyl 3-guanidino-4-methylbenzoate Nitrate, Nilotinib Impurity 1, Nilotinib Impurity N1 Nitrate salt, Benzoic acid, 3-[(aminoiminomethyl)amino]-4-methyl-, methyl ester, nitrate (1:1)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib KSM Nitrate Impurity?

The CAS Registry Number of Nilotinib KSM Nitrate Impurity is 1025716-99-7. It is also known as 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid methyl ester nitrate, 4-methyl-3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid methyl ester nitrate, Methyl 3-guanidino-4-methylbenzoate Nitrate.

What is the molecular formula and molecular weight of Nilotinib KSM Nitrate Impurity?

Nilotinib KSM Nitrate Impurity has the molecular formula C10H14N4O5 and a molecular weight of 270.24 g/mol.

What is Nilotinib KSM Nitrate Impurity used for?

Nilotinib KSM Nitrate Impurity is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib KSM Nitrate Impurity can I order?

We supply Nilotinib KSM Nitrate Impurity in Reference Standard (95%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib KSM Nitrate Impurity?

Yes. Every lot of Nilotinib KSM Nitrate Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib KSM Nitrate Impurity be shipped internationally?

Yes. Nilotinib KSM Nitrate Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.