Escitalopram EP Impurity E

Name: Escitalopram EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-006373

About Escitalopram EP Impurity E

Escitalopram EP Impurity E (CAS 103146-25-4) is a pharmacopeial impurity of Escitalopram offered by Vaqora Chemicals. With the molecular formula C20H23FN2O2, it has a molar mass of 342.4 g/mol. Its systematic (IUPAC) name is 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile. It is also known as Citadiol or Citalopram Dihydroxy Impurity.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Escitalopram, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Escitalopram EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Escitalopram

View every impurity, metabolite and intermediate we list for Escitalopram.

Escitalopram impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Escitalopram EP Impurity E
Catalogue No.	VQ-006373
CAS Number	103146-25-4
Other CAS	103146-26-5, 717133-25-0
IUPAC name	4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile
Molecular formula	C₂₀H₂₃FN₂O₂
Molecular weight	342.4 g/mol
Exact mass	342.1744
Grade	Reference Standard
HSN code	38229090
InChIKey	GNULRNVWXYXBQY-UHFFFAOYSA-N
SMILES	CN(C)CCCC(C1=CC=C(C=C1)F)(C2=C(C=C(C=C2)C#N)CO)O
PubChem CID	10132164

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 5
TPSA	67.5 Å²
Synonyms	4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile, 4-[4-(Dimethylamino)-1-(4′-fluorophenyl)-1-[hydroxy]butyl]-3-(hydroxymethyl)benzonitrile, Citadiol, Citalopram Dihydroxy Impurity, 4-(4-(Dimethylamino)-1-(4'-fluorophenyl)-1-(hydroxy)butyl)-3-(hydroxymethyl)benzonitrile, 4-(4-Dimethylamino-1-(4'-fluorophenyl)-1-hydroxy-1-butyl)-3-hydroxymethyl benzonitrile, Benzonitrile, 4-(4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-, CTD compound, (+/-)-Citadiol, Citadiol, (+/-)-, Escitalopram Impurity 2, (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P321, P330, P333 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Escitalopram EP Impurity E?

The CAS Registry Number of Escitalopram EP Impurity E is 103146-25-4. It is also known as 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile, 4-[4-(Dimethylamino)-1-(4′-fluorophenyl)-1-[hydroxy]butyl]-3-(hydroxymethyl)benzonitrile, Citadiol.

What is the molecular formula and molecular weight of Escitalopram EP Impurity E?

Escitalopram EP Impurity E has the molecular formula C20H23FN2O2 and a molecular weight of 342.4 g/mol. Its IUPAC name is 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile.

What is Escitalopram EP Impurity E used for?

Escitalopram EP Impurity E is supplied as a characterised reference material related to Escitalopram. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Escitalopram EP Impurity E can I order?

We supply Escitalopram EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Escitalopram EP Impurity E?

Yes. Every lot of Escitalopram EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Escitalopram EP Impurity E be shipped internationally?

Yes. Escitalopram EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.