Letrozole Impurity-D

Name: Letrozole Impurity-D
Brand: Vaqora Chemicals
SKU: VQ-005176

About Letrozole Impurity-D

Vaqora Chemicals supplies Letrozole Impurity-D, an impurity of Letrozole registered under CAS number 10466-37-2. The compound has the formula C15H10N2, corresponding to a molecular weight of 218.25 g/mol. Its systematic (IUPAC) name is 4-[(4-cyanophenyl)methyl]benzonitrile. Alternative names: 4,4'-Methylenebis[benzonitrile] and 4,4'-Methylenedibenzonitrile.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Letrozole impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Letrozole Impurity-D in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Letrozole

View every impurity, metabolite and intermediate we list for Letrozole.

Letrozole impurities

Specifications & identifiers

Chemical identifiers
Product name	Letrozole Impurity-D
Catalogue No.	VQ-005176
CAS Number	10466-37-2
IUPAC name	4-[(4-cyanophenyl)methyl]benzonitrile
Molecular formula	C₁₅H₁₀N₂
Molecular weight	218.25 g/mol
Exact mass	218.0844
Grade	Reference Standard
HSN code	38229090
InChIKey	QHPFUQAZWHBITN-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1CC2=CC=C(C=C2)C#N)C#N
PubChem CID	300442

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 2
TPSA	47.6 Å²
Synonyms	4,4'-Methylenebis[benzonitrile], 4,4'-Methylenedibenzonitrile, 4,4'-(methylene)bis-benzonitrile, Letrozole Impurity D, 4,4'-Dicyanodiphenylmethane, 4,4'-Methylenebisbenzonitrile, 4,4'-(1-methylene) bis-Benzonitrile, 4,4'-(1-methylene), Letrozole impurity 01, 4,4''-Methylenedibenzonitrile, Benzonitrile,4,4'-methylenebis-, 4,4'-(1-Methylene)bis-benzonitrile

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Letrozole Impurity-D?

The CAS Registry Number of Letrozole Impurity-D is 10466-37-2. It is also known as 4,4'-Methylenebis[benzonitrile], 4,4'-Methylenedibenzonitrile, 4,4'-(methylene)bis-benzonitrile.

What is the molecular formula and molecular weight of Letrozole Impurity-D?

Letrozole Impurity-D has the molecular formula C15H10N2 and a molecular weight of 218.25 g/mol. Its IUPAC name is 4-[(4-cyanophenyl)methyl]benzonitrile.

What is Letrozole Impurity-D used for?

Letrozole Impurity-D is supplied as a characterised reference material related to Letrozole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Letrozole Impurity-D can I order?

We supply Letrozole Impurity-D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Letrozole Impurity-D?

Yes. Every lot of Letrozole Impurity-D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Letrozole Impurity-D be shipped internationally?

Yes. Letrozole Impurity-D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.