4-Hydroxy-Teriflunomide

About 4-Hydroxy-Teriflunomide

4-Hydroxy-Teriflunomide is a metabolite or degradation product of Teriflunomide carrying the CAS registry number 1058722-45-4. The compound has the formula C12H9F3N2O3, corresponding to a molecular weight of 286.21 g/mol. Systematically, it is named (Z)-2-cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide. Alternative names: Methyl-OH HMR1726 and Teriflunomide metabolite M7.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Teriflunomide, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4-Hydroxy-Teriflunomide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Teriflunomide

View every impurity, metabolite and intermediate we list for Teriflunomide.

Teriflunomide impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy-Teriflunomide
Catalogue No.	VQ-031467
CAS Number	1058722-45-4
IUPAC name	(Z)-2-cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
Molecular formula	C₁₂H₉F₃N₂O₃
Molecular weight	286.21 g/mol
Exact mass	286.0565
Grade	Reference Standard
HSN code	38229090
InChIKey	WHYQOFDUXDGMTM-KTKRTIGZSA-N
SMILES	C1=CC(=CC=C1C(F)(F)F)NC(=O)/C(=C(/CO)\O)/C#N
PubChem CID	125392027

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	3 / 7
TPSA	93.4 Å²
Synonyms	Methyl-OH HMR1726, Teriflunomide metabolite M7, (2Z)-2-Cyano-3,4-dihydroxy-N-(4-(trifluoromethyl)phenyl)-2-butenamide, 2-Butenamide, 2-cyano-3,4-dihydroxy-N-(4-(trifluoromethyl)phenyl)-, (2Z)-, (Z)-2-cyano-3,4-dihydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy-Teriflunomide?

The CAS Registry Number of 4-Hydroxy-Teriflunomide is 1058722-45-4. It is also known as Methyl-OH HMR1726, Teriflunomide metabolite M7, (2Z)-2-Cyano-3,4-dihydroxy-N-(4-(trifluoromethyl)phenyl)-2-butenamide.

What is the molecular formula and molecular weight of 4-Hydroxy-Teriflunomide?

4-Hydroxy-Teriflunomide has the molecular formula C12H9F3N2O3 and a molecular weight of 286.21 g/mol. Its IUPAC name is (Z)-2-cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide.

What is 4-Hydroxy-Teriflunomide used for?

4-Hydroxy-Teriflunomide is supplied as a characterised reference material related to Teriflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy-Teriflunomide can I order?

We supply 4-Hydroxy-Teriflunomide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy-Teriflunomide?

Yes. Every lot of 4-Hydroxy-Teriflunomide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy-Teriflunomide be shipped internationally?

Yes. We export 4-Hydroxy-Teriflunomide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.