Apixaban Methyl Ester Impurity

About Apixaban Methyl Ester Impurity

Apixaban Methyl Ester Impurity is an impurity of Apixaban carrying the CAS registry number 1074365-84-6 with a typical assay of 98%. Its molecular formula is C26H26N4O5 and its molecular weight is 474.5 g/mol. It is also known as Apixaban Related Compound E or Apixaban Impurity 6.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Apixaban to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Apixaban Methyl Ester Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apixaban

View every impurity, metabolite and intermediate we list for Apixaban.

Apixaban impurities

Specifications & identifiers

Chemical identifiers
Product name	Apixaban Methyl Ester Impurity
Catalogue No.	VQ-004423
CAS Number	1074365-84-6
IUPAC name	methyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxylate
Molecular formula	C₂₆H₂₆N₄O₅
Molecular weight	474.5 g/mol
Exact mass	474.1903
Grade	Reference Standard
Purity / assay	98%
HSN code	38229090
InChIKey	IHFSYYKSFUFOTJ-UHFFFAOYSA-N
SMILES	COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)OC
PubChem CID	56956411

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	0 / 6
TPSA	94 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Apixaban Methyl Ester Impurity?

The CAS Registry Number of Apixaban Methyl Ester Impurity is 1074365-84-6. It is also known as Apixaban Related Compound E, Apixaban Impurity 6, Apixaban Impurity Bms-719288.

What is the molecular formula and molecular weight of Apixaban Methyl Ester Impurity?

Apixaban Methyl Ester Impurity has the molecular formula C26H26N4O5 and a molecular weight of 474.5 g/mol. Its IUPAC name is methyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxylate.

What is Apixaban Methyl Ester Impurity used for?

Apixaban Methyl Ester Impurity is supplied as a characterised reference material related to Apixaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Apixaban Methyl Ester Impurity can I order?

We supply Apixaban Methyl Ester Impurity in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Apixaban Methyl Ester Impurity?

Yes. Every lot of Apixaban Methyl Ester Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Apixaban Methyl Ester Impurity be shipped internationally?

Yes. We export Apixaban Methyl Ester Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.