Esomeprazole Impurity B
Synonyms: 2-[[(3,5-Dimethyl-2-pyridinyl)methyl]sulfinyl]-6-methoxy-1H-benzimidazole · 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole · 2-(((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole · 4-Desmethoxy Omeprazole
Esomeprazole Impurity B (CAS 110374-16-8) – Esomeprazole impurity standard, 90.12%. C16H17N3O2S, MW 315.4. Vaqora Chemicals: COA, global shipping.
About Esomeprazole Impurity B
Esomeprazole Impurity B (CAS 110374-16-8) is an impurity of Esomeprazole offered by Vaqora Chemicals with a typical assay of 90.12%. Formula C16H17N3O2S, molecular weight 315.4 g/mol. Systematically, it is named 2-[(3,5-dimethyl-2-pyridinyl)methylsulfinyl]-6-methoxy-1H-benzimidazole. Common synonyms include 4-Desmethoxy Omeprazole and Omeprazole EP Impurity B.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.
As a characterised impurity of Esomeprazole, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies Esomeprazole Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Esomeprazole.
Esomeprazole impuritiesSpecifications & identifiers
| Product name | Esomeprazole Impurity B |
|---|---|
| Catalogue No. | VQ-004931 |
| CAS Number | 110374-16-8 |
| IUPAC name | 2-[(3,5-dimethyl-2-pyridinyl)methylsulfinyl]-6-methoxy-1H-benzimidazole |
| Molecular formula | C16H17N3O2S |
| Molecular weight | 315.4 g/mol |
| Exact mass | 315.1041 |
| Grade | Reference Standard |
| Purity / assay | 90.12% |
| HSN code | 38229090 |
| InChIKey | ZMXZYNHJPJEPAE-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(N=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC)C |
| PubChem CID | 46781146 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.3 |
| H-bond donors / acceptors | 1 / 5 |
| TPSA | 87.1 Ų |
| Synonyms | 2-[[(3,5-Dimethyl-2-pyridinyl)methyl]sulfinyl]-6-methoxy-1H-benzimidazole, 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole, 2-(((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole, 4-Desmethoxy Omeprazole, Omeprazole EP Impurity B, Omeprazole Impurity B, 1H-Benzimidazole, 2-(((3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-6-methoxy-, 2-((RS)-((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole, Omeprazole magnesium impurity B, 2-[(3,5-dimethylpyridin-2-yl)methylsulfinyl]-6-methoxy-1H-benzimidazole, 5-Methoxy-2-[(3,5-dimethyl-2-pyridinyl)-methylsulfinyl]-benzimidazole, (+/-)-2-(((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H302Harmful if swallowedH315Causes skin irritationH411Toxic to aquatic life with long lasting effects
Precautionary statements: P264, P270, P273, P280, P301 + P317, P302 + P352, P321, P330, P332 + P317, P362 + P364, P391, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Esomeprazole Impurity B?
The CAS Registry Number of Esomeprazole Impurity B is 110374-16-8. It is also known as 2-[[(3,5-Dimethyl-2-pyridinyl)methyl]sulfinyl]-6-methoxy-1H-benzimidazole, 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole, 2-(((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole.
What is the molecular formula and molecular weight of Esomeprazole Impurity B?
Esomeprazole Impurity B has the molecular formula C16H17N3O2S and a molecular weight of 315.4 g/mol. Its IUPAC name is 2-[(3,5-dimethyl-2-pyridinyl)methylsulfinyl]-6-methoxy-1H-benzimidazole.
What is Esomeprazole Impurity B used for?
Esomeprazole Impurity B is supplied as a characterised reference material related to Esomeprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Esomeprazole Impurity B can I order?
We supply Esomeprazole Impurity B in Reference Standard (90.12%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Esomeprazole Impurity B?
Yes. Every lot of Esomeprazole Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Esomeprazole Impurity B be shipped internationally?
Yes. Esomeprazole Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Esomeprazole Impurity B
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