Esomeprazole EP Impurity A

Name: Esomeprazole EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-006375

About Esomeprazole EP Impurity A

Esomeprazole EP Impurity A (CAS 37052-78-1) is a pharmacopeial impurity of Esomeprazole offered by Vaqora Chemicals. Formula C8H8N2OS, molecular weight 180.23 g/mol. Its systematic (IUPAC) name is 5-methoxy-1,3-dihydrobenzimidazole-2-thione. Alternative names: 2-Mercapto-5-methoxy-1H-benzimidazole and 5-Methoxy-1H-benzimidazole-2-thiol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Esomeprazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Esomeprazole

View every impurity, metabolite and intermediate we list for Esomeprazole.

Esomeprazole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Esomeprazole EP Impurity A
Catalogue No.	VQ-006375
CAS Number	37052-78-1
Other CAS	148201-63-2
IUPAC name	5-methoxy-1,3-dihydrobenzimidazole-2-thione
Molecular formula	C₈H₈N₂OS
Molecular weight	180.23 g/mol
Exact mass	180.0357
Grade	Reference Standard
HSN code	38229090
InChIKey	KOFBRZWVWJCLGM-UHFFFAOYSA-N
SMILES	COC1=CC2=C(C=C1)NC(=S)N2
PubChem CID	665603

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	2 / 2
TPSA	65.4 Å²
Synonyms	1,3-Dihydro-5-methoxy-2H-benzimidazole-2-thione, 2-Mercapto-5-methoxy-1H-benzimidazole, 5-Methoxy-1H-benzimidazole-2-thiol, 2-Mercapto-5-methoxybenzimidazole, 5-Methoxy-2-benzimidazolethiol, Omeprazole Related Compound B (USP), Omeprazole Impurity A, 5-Methoxy-2-mercaptobenzimidazole, 2H-Benzimidazole-2-thione, 1,3-dihydro-5-methoxy-, 5-methoxy-1H-benzo[d]imidazole-2(3H)-thione, 5-methoxy-1H-benzo[d]imidazole-2-thiol, 5-methoxy-1H-1,3-benzodiazole-2-thiol

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H370Causes damage to organs
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P260, P261, P264, P264 + P265, P270, P271, P272, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P308 + P316, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 37052-78-1

Extra Pure

2-Mercapto-5-methoxybenzimidazole, extra pure >98%

CAS: 37052-78-1
Formula: C₈H₈N₂OS
MW: 180.23 g/mol

VQ-045931

Frequently asked questions

What is the CAS number of Esomeprazole EP Impurity A?

The CAS Registry Number of Esomeprazole EP Impurity A is 37052-78-1. It is also known as 1,3-Dihydro-5-methoxy-2H-benzimidazole-2-thione, 2-Mercapto-5-methoxy-1H-benzimidazole, 5-Methoxy-1H-benzimidazole-2-thiol.

What is the molecular formula and molecular weight of Esomeprazole EP Impurity A?

Esomeprazole EP Impurity A has the molecular formula C8H8N2OS and a molecular weight of 180.23 g/mol. Its IUPAC name is 5-methoxy-1,3-dihydrobenzimidazole-2-thione.

What is Esomeprazole EP Impurity A used for?

Esomeprazole EP Impurity A is supplied as a characterised reference material related to Esomeprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Esomeprazole EP Impurity A can I order?

We supply Esomeprazole EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Esomeprazole EP Impurity A?

Yes. Every lot of Esomeprazole EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Esomeprazole EP Impurity A be shipped internationally?

Yes. Esomeprazole EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.