5,8-Epoxy-13-cis Retinoic Acid

Name: 5,8-Epoxy-13-cis Retinoic Acid
Brand: Vaqora Chemicals
SKU: VQ-031289

About 5,8-Epoxy-13-cis Retinoic Acid

Listed under CAS 112018-12-9, 5,8-Epoxy-13-cis Retinoic Acid is a metabolite or degradation product of Isotretinoin available from Vaqora Chemicals. With the molecular formula C20H28O3, it has a molar mass of 316.4 g/mol. The IUPAC name is (2Z,4E,6E)-7-(4,4,7a-trimethyl-2,5,6,7-tetrahydro-1-benzofuran-2-yl)-3-methylocta-2,4,6-trienoic acid. Common synonyms include 5,8-Epoxytretinoin, (13Z)- and 5,8-Epoxy-5,8-dihydro retinoic acid, (13Z)-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Isotretinoin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5,8-Epoxy-13-cis Retinoic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	5,8-Epoxy-13-cis Retinoic Acid
Catalogue No.	VQ-031289
CAS Number	112018-12-9
IUPAC name	(2Z,4E,6E)-7-(4,4,7a-trimethyl-2,5,6,7-tetrahydro-1-benzofuran-2-yl)-3-methylocta-2,4,6-trienoic acid
Molecular formula	C₂₀H₂₈O₃
Molecular weight	316.4 g/mol
Exact mass	316.2038
Grade	Reference Standard
HSN code	38229090
InChIKey	QDOSIDVGVRAXSE-DYIZZJGFSA-N
SMILES	C/C(=C/C(=O)O)/C=C/C=C(\C)/C1C=C2C(CCCC2(O1)C)(C)C
PubChem CID	71316382

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5,8-Epoxy-13-cis Retinoic Acid?

The CAS Registry Number of 5,8-Epoxy-13-cis Retinoic Acid is 112018-12-9. It is also known as 5,8-Epoxy-13-cis Retinoic Acid (Mixture of Diastereomers), 5,8-Epoxytretinoin, (13Z)-, 5,8-Epoxy-5,8-dihydro retinoic acid, (13Z)-.

What is the molecular formula and molecular weight of 5,8-Epoxy-13-cis Retinoic Acid?

5,8-Epoxy-13-cis Retinoic Acid has the molecular formula C20H28O3 and a molecular weight of 316.4 g/mol. Its IUPAC name is (2Z,4E,6E)-7-(4,4,7a-trimethyl-2,5,6,7-tetrahydro-1-benzofuran-2-yl)-3-methylocta-2,4,6-trienoic acid.

What is 5,8-Epoxy-13-cis Retinoic Acid used for?

5,8-Epoxy-13-cis Retinoic Acid is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5,8-Epoxy-13-cis Retinoic Acid can I order?

We supply 5,8-Epoxy-13-cis Retinoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5,8-Epoxy-13-cis Retinoic Acid?

Yes. Every lot of 5,8-Epoxy-13-cis Retinoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5,8-Epoxy-13-cis Retinoic Acid be shipped internationally?

Yes. We export 5,8-Epoxy-13-cis Retinoic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.