tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydrox… 1127490-74-7

Name: tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
Brand: Vaqora Chemicals
SKU: VQ-042068

About tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate

tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate (CAS 1127490-74-7) is a metabolite or degradation product of Sacubitril offered by Vaqora Chemicals. Its molecular formula is C20H25NO3 and its molecular weight is 327.4 g/mol. Systematically, it is named tert-butyl N-[1-hydroxy-3-(4-phenylphenyl)propan-2-yl]carbamate. Alternative names: LCZ696 InteMediate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Sacubitril, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
Catalogue No.	VQ-042068
CAS Number	1127490-74-7
IUPAC name	tert-butyl N-[1-hydroxy-3-(4-phenylphenyl)propan-2-yl]carbamate
Molecular formula	C₂₀H₂₅NO₃
Molecular weight	327.4 g/mol
Exact mass	327.1834
Grade	Reference Standard
HSN code	38229090
InChIKey	TYQICOFAZDVKMK-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)C2=CC=CC=C2)CO
PubChem CID	19427706

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	2 / 3
TPSA	58.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate?

The CAS Registry Number of tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate is 1127490-74-7. It is also known as LCZ696 InteMediate, tert-butyl N-[1-(hydroxymethyl)-2-(4-phenylphenyl)ethyl]carbamate, 1,1-Dimethylethyl N-[2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamate.

What is the molecular formula and molecular weight of tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate?

tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate has the molecular formula C20H25NO3 and a molecular weight of 327.4 g/mol. Its IUPAC name is tert-butyl N-[1-hydroxy-3-(4-phenylphenyl)propan-2-yl]carbamate.

What is tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate used for?

tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate can I order?

We supply tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate?

Yes. Every lot of tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate be shipped internationally?

Yes. We export tert-Butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.