Amifostine Trihydrate

About Amifostine Trihydrate

Amifostine Trihydrate is a high-purity reference standard of Amifostine carrying the CAS registry number 112901-68-5. The compound has the formula C5H21N2O6PS, corresponding to a molecular weight of 268.27 g/mol. Alternative names: Anifostine trihydrate and Ethyol trihydrate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Laboratories use this Amifostine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Amifostine

View every impurity, metabolite and intermediate we list for Amifostine.

Amifostine impurities

Specifications & identifiers

Chemical identifiers
Product name	Amifostine Trihydrate
Catalogue No.	VQ-043454
CAS Number	112901-68-5
IUPAC name	2-(3-aminopropylamino)ethylsulfanylphosphonic acid;trihydrate
Molecular formula	C₅H₂₁N₂O₆PS
Molecular weight	268.27 g/mol
Exact mass	268.0858
Grade	Reference Standard
HSN code	38229090
InChIKey	TXQPXJKRNHJWAX-UHFFFAOYSA-N
SMILES	C(CN)CNCCSP(=O)(O)O.O.O.O
PubChem CID	148139

Physical properties
Physical form	Solid
H-bond donors / acceptors	7 / 9
TPSA	124 Å²
Synonyms	Anifostine trihydrate, S-(2-((3-aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate, Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrogen phosphate (ester),trihydrate, 2-(3-aminopropylamino)ethylsulfanylphosphonic acid trihydrate, S-(2-((3-Aminopropyl)amino)ethyl) dihydrogen phosphorothioate, trihydrate, Ethyol trihydrate, S-[2-[(3-Aminopropyl)amino]ethyl] dihydrogen phosphorothioate, trihydrate, S-(2-((3-Aminopropyl)Amino)Ethyl)O,O-DihydrogenPhosphorothioateTrihydrate, Ethanethiol, 2-[(3-aminopropyl)amino]-, 1-(dihydrogen phosphate), hydrate (1:3), S-{2-[(3-Aminopropyl)amino]ethyl} dihydrogen phosphorothioate--water (1/3)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amifostine Trihydrate?

The CAS Registry Number of Amifostine Trihydrate is 112901-68-5. It is also known as Anifostine trihydrate, S-(2-((3-aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate, Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrogen phosphate (ester),trihydrate.

What is the molecular formula and molecular weight of Amifostine Trihydrate?

Amifostine Trihydrate has the molecular formula C5H21N2O6PS and a molecular weight of 268.27 g/mol.

What is Amifostine Trihydrate used for?

Amifostine Trihydrate is supplied as a characterised reference material related to Amifostine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amifostine Trihydrate can I order?

We supply Amifostine Trihydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amifostine Trihydrate?

Yes. Every lot of Amifostine Trihydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amifostine Trihydrate be shipped internationally?

Yes. Amifostine Trihydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.