1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hyd… 1129683-83-5

About 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is a metabolite or degradation product of Sorafenib carrying the CAS registry number 1129683-83-5. Its molecular formula is C14H10ClF3N2O2 and its molecular weight is 330.69 g/mol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Sorafenib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea
Catalogue No.	VQ-032639
CAS Number	1129683-83-5
IUPAC name	1-[4-chloro-3-(trifluoromethyl)phenyl]-3-(4-hydroxyphenyl)urea
Molecular formula	C₁₄H₁₀ClF₃N₂O₂
Molecular weight	330.69 g/mol
Exact mass	330.0383
Grade	Reference Standard
HSN code	38229090
InChIKey	QKJVYCOMRSLHGX-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1NC(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F)O
PubChem CID	25221150

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	3 / 5
TPSA	61.4 Å²
Synonyms	N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea, 1-(4-chloro-3-(trifluromethyl)phenyl)-3-(4-hydroxyphenyl)urea, 3-[4-chloro-3-(trifluoromethyl)phenyl]-1-(4-hydroxyphenyl)urea, N-(4-chloro-3 -(trifluoromethyl)phenyl)-N'-(4-hydroxylphenyl)urea, Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea?

The CAS Registry Number of 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is 1129683-83-5. It is also known as N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea, 1-(4-chloro-3-(trifluromethyl)phenyl)-3-(4-hydroxyphenyl)urea, 3-[4-chloro-3-(trifluoromethyl)phenyl]-1-(4-hydroxyphenyl)urea.

What is the molecular formula and molecular weight of 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea?

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea has the molecular formula C14H10ClF3N2O2 and a molecular weight of 330.69 g/mol. Its IUPAC name is 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-(4-hydroxyphenyl)urea.

What is 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea used for?

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea can I order?

We supply 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea?

Yes. Every lot of 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea be shipped internationally?

Yes. We export 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.