Levocetirizine-d4

About Levocetirizine-d4

Levocetirizine-d4 is a stable isotope labelled analogue related to Levocetirizine carrying the CAS registry number 1133210-23-7. Its molecular formula is C21H25ClN2O3 and its molecular weight is 392.9 g/mol. The IUPAC name is 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]-1,1,2,2-tetradeuterioethoxy]acetic acid. Common synonyms include Levocetirizine-D4 Dihydrochloride and (R)-Cetirizine-d4 Dihydrochloride.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Levocetirizine

View every impurity, metabolite and intermediate we list for Levocetirizine.

Levocetirizine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Levocetirizine-d4
Catalogue No.	VQ-037995
CAS Number	1133210-23-7
IUPAC name	2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]-1,1,2,2-tetradeuterioethoxy]acetic acid
Molecular formula	C₂₁H₂₅ClN₂O₃
Molecular weight	392.9 g/mol
Exact mass	392.1805
Grade	Reference Standard
HSN code	38229090
InChIKey	ZKLPARSLTMPFCP-KNFDVUFYSA-N
SMILES	[2H]C([2H])(C([2H])([2H])OCC(=O)O)N1CCN(CC1)[C@H](C2=CC=CC=C2)C3=CC=C(C=C3)Cl
PubChem CID	25230784

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 5
TPSA	53 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levocetirizine-d4?

The CAS Registry Number of Levocetirizine-d4 is 1133210-23-7. It is also known as Levocetirizine-D4 Dihydrochloride, (R)-Cetirizine-d4 Dihydrochloride.

What is the molecular formula and molecular weight of Levocetirizine-d4?

Levocetirizine-d4 has the molecular formula C21H25ClN2O3 and a molecular weight of 392.9 g/mol. Its IUPAC name is 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]-1,1,2,2-tetradeuterioethoxy]acetic acid.

What is Levocetirizine-d4 used for?

Levocetirizine-d4 is supplied as a characterised reference material related to Levocetirizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levocetirizine-d4 can I order?

We supply Levocetirizine-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levocetirizine-d4?

Yes. Every lot of Levocetirizine-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levocetirizine-d4 be shipped internationally?

Yes. We export Levocetirizine-d4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.