Cetirizine EP Impurity B

Name: Cetirizine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-006295

About Cetirizine EP Impurity B

Listed under CAS 113740-61-7, Cetirizine EP Impurity B is a pharmacopeial impurity of Cetirizine available from Vaqora Chemicals. With the molecular formula C19H21ClN2O2, it has a molar mass of 344.8 g/mol. Its systematic (IUPAC) name is 2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]acetic acid. Common synonyms include Levocetirizine Impurity 3 and De(carboxymethoxy) Cetirizine Acetic Acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Cetirizine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cetirizine EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cetirizine

View every impurity, metabolite and intermediate we list for Cetirizine.

Cetirizine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cetirizine EP Impurity B
Catalogue No.	VQ-006295
CAS Number	113740-61-7
Other CAS	1000690-91-4
IUPAC name	2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]acetic acid
Molecular formula	C₁₉H₂₁ClN₂O₂
Molecular weight	344.8 g/mol
Exact mass	344.1292
Grade	Reference Standard
HSN code	38229090
InChIKey	NBQBQRKLQXVPIS-UHFFFAOYSA-N
SMILES	C1CN(CCN1CC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
PubChem CID	25063264

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	1 / 4
TPSA	43.8 Å²
Synonyms	4-[(4-chlorophenyl)phenylmethyl]-1-piperazin acetic acid, Levocetirizine Impurity 3, De(carboxymethoxy) Cetirizine Acetic Acid, Cetirizine acetic acid, 2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid, Cetirizine Impurity B, 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineacetic acid, 4-((4-Chlorophenyl)phenylmethyl)-1-piperazineacetic Acid, iperazineacetic acid, 4-[(4- chlorophenyl)phenylMethyl]-, Cetirizine Impurity N19, Cetirizine impurity B 2HCL, [4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]acetic acid

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H400Very toxic to aquatic life

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cetirizine EP Impurity B?

The CAS Registry Number of Cetirizine EP Impurity B is 113740-61-7. It is also known as 4-[(4-chlorophenyl)phenylmethyl]-1-piperazin acetic acid, Levocetirizine Impurity 3, De(carboxymethoxy) Cetirizine Acetic Acid.

What is the molecular formula and molecular weight of Cetirizine EP Impurity B?

Cetirizine EP Impurity B has the molecular formula C19H21ClN2O2 and a molecular weight of 344.8 g/mol. Its IUPAC name is 2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]acetic acid.

What is Cetirizine EP Impurity B used for?

Cetirizine EP Impurity B is supplied as a characterised reference material related to Cetirizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cetirizine EP Impurity B can I order?

We supply Cetirizine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cetirizine EP Impurity B?

Yes. Every lot of Cetirizine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cetirizine EP Impurity B be shipped internationally?

Yes. Cetirizine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.