Temozolomide EP Impurity B

About Temozolomide EP Impurity B

Temozolomide EP Impurity B is a pharmacopeial impurity of Temozolomide carrying the CAS registry number 113942-30-6. With the molecular formula C6H5N5O3, it has a molar mass of 195.14 g/mol. The IUPAC name is 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid. Common synonyms include Temozolomide Acid and Temozolomide - Impurity B.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

This Temozolomide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Temozolomide EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Temozolomide

View every impurity, metabolite and intermediate we list for Temozolomide.

Temozolomide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Temozolomide EP Impurity B
Catalogue No.	VQ-021348
CAS Number	113942-30-6
IUPAC name	3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid
Molecular formula	C₆H₅N₅O₃
Molecular weight	195.14 g/mol
Exact mass	195.0392
Grade	Reference Standard
HSN code	38229090
InChIKey	VVTMIOYTNALQAW-UHFFFAOYSA-N
SMILES	CN1C(=O)N2C=NC(=C2N=N1)C(=O)O
PubChem CID	11830328

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	1 / 6
TPSA	100 Å²
Synonyms	Temozolomide Acid, Temozolomide - Impurity B, 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid, Temozolomide-8-carboxylic Acid, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid, 3,4-dihydro-3-methyl-4-oxo-, 3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxylic acid, Imidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxylic acid, 3,4-dihydro-3-methyl-4-oxo-, 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d]-[1,2,3,5]tetrazine-8-carboxylic acid, 3-Methyl-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid, 3-Methyl-4-oxo-3,4, 3-Methyl-4-oxo-34-dihydroimidazo[51-d][1235]tetrazine-8-carboxylic acid, 3-methyl-4-oxo-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Temozolomide EP Impurity B?

The CAS Registry Number of Temozolomide EP Impurity B is 113942-30-6. It is also known as Temozolomide Acid, Temozolomide - Impurity B, 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid.

What is the molecular formula and molecular weight of Temozolomide EP Impurity B?

Temozolomide EP Impurity B has the molecular formula C6H5N5O3 and a molecular weight of 195.14 g/mol. Its IUPAC name is 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid.

What is Temozolomide EP Impurity B used for?

Temozolomide EP Impurity B is supplied as a characterised reference material related to Temozolomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Temozolomide EP Impurity B can I order?

We supply Temozolomide EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Temozolomide EP Impurity B?

Yes. Every lot of Temozolomide EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Temozolomide EP Impurity B be shipped internationally?

Yes. Temozolomide EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.