Bortezomib Impurity F (Freebase)

Name: Bortezomib Impurity F (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-004539

About Bortezomib Impurity F (Freebase)

Vaqora Chemicals supplies Bortezomib Impurity F (Freebase), an impurity of Bortezomib registered under CAS number 114457-94-2 at a purity of 99.44%. With the molecular formula C14H13N3O3, it has a molar mass of 271.27 g/mol. Its systematic (IUPAC) name is (2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoic acid. Common synonyms include N-(2-pyrazinylcarbonyl)-L-phenylalanine and N-Pyrazinylcarbonyl-L-phenylalanine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Bortezomib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg and 50 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bortezomib

View every impurity, metabolite and intermediate we list for Bortezomib.

Bortezomib impurities

Specifications & identifiers

Chemical identifiers
Product name	Bortezomib Impurity F (Freebase)
Catalogue No.	VQ-004539
CAS Number	114457-94-2
Other CAS	1093959-75-1
IUPAC name	(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoic acid
Molecular formula	C₁₄H₁₃N₃O₃
Molecular weight	271.27 g/mol
Exact mass	271.0957
Grade	Reference Standard
Purity / assay	99.44%
HSN code	38229090
InChIKey	DWYZPDHMMZGQAP-NSHDSACASA-N
SMILES	C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)C2=NC=CN=C2
PubChem CID	15042559

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	2 / 5
TPSA	92.2 Å²
Synonyms	(S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid, (S)-3-Phenyl-2-[[(pyrazin-2-yl)carbonyl]amino]propanoic acid, N-(2-pyrazinylcarbonyl)-L-phenylalanine, N-Pyrazinylcarbonyl-L-phenylalanine, Bortezomib Impurity F, Bortezomib Acid Analog, Gemcitabine Specified Impurity 1, N-(Pyrazinylcarbonyl)-L-phenylalanine, (S)-3-Phenyl-2-[(pyrazin-2-ylcarbonyl)amino] propanoic acid, L-Phenylalanine, N-(2-pyrazinylcarbonyl)-, Bortezomib (m4), Bortezomib Impurity D

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bortezomib Impurity F (Freebase)?

The CAS Registry Number of Bortezomib Impurity F (Freebase) is 114457-94-2. It is also known as (S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid, (S)-3-Phenyl-2-[[(pyrazin-2-yl)carbonyl]amino]propanoic acid, N-(2-pyrazinylcarbonyl)-L-phenylalanine.

What is the molecular formula and molecular weight of Bortezomib Impurity F (Freebase)?

Bortezomib Impurity F (Freebase) has the molecular formula C14H13N3O3 and a molecular weight of 271.27 g/mol. Its IUPAC name is (2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoic acid.

What is Bortezomib Impurity F (Freebase) used for?

Bortezomib Impurity F (Freebase) is supplied as a characterised reference material related to Bortezomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bortezomib Impurity F (Freebase) can I order?

We supply Bortezomib Impurity F (Freebase) in Reference Standard (99.44%) grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bortezomib Impurity F (Freebase)?

Yes. Every lot of Bortezomib Impurity F (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bortezomib Impurity F (Freebase) be shipped internationally?

Yes. We export Bortezomib Impurity F (Freebase) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.