Baricitinib Impurity 6 (Stage-3)

About Baricitinib Impurity 6 (Stage-3)

Baricitinib Impurity 6 (Stage-3) is an impurity of Baricitinib carrying the CAS registry number 1146629-77-7 at a purity of 95%. With the molecular formula C15H17N5O2, it has a molar mass of 299.33 g/mol. Systematically, it is named [4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate. Alternative names: Baricitinib Impurity 42.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Baricitinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Baricitinib Impurity 6 (Stage-3) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Baricitinib

View every impurity, metabolite and intermediate we list for Baricitinib.

Baricitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Baricitinib Impurity 6 (Stage-3)
Catalogue No.	VQ-004487
CAS Number	1146629-77-7
IUPAC name	[4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate
Molecular formula	C₁₅H₁₇N₅O₂
Molecular weight	299.33 g/mol
Exact mass	299.1382
Grade	Reference Standard
Purity / assay	95%
HSN code	38229090
InChIKey	CPGIWDOJHYCMRW-UHFFFAOYSA-N
SMILES	CC(C)(C)C(=O)OCN1C=CC2=C(N=CN=C21)C3=CNN=C3
PubChem CID	57868869

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 5
TPSA	85.7 Å²
Synonyms	(4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate, [4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate, [4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate, (4-(1H-Pyrazol-4-yl)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)methyl pivalate, Baricitinib Impurity 42, [4-(4-Pyrazolyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl Pivalate, (4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methylpivalate, [4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl ..., 4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin070yl]methyl Pivalate, [4-(1H-pyrazole-4-yl) -7h-pyrrorole [2,3-D] pyrimidine-7-yl] methyl tevalate ester, 2,2-Dimethyl-propionic acid 4-(1H-pyrazol-4-yl)-pyrrolo[2,3-d]pyrimidin-7-ylmethyl ester, 4- (1H pyrazole-4-yl) -7H pyrrolo [2,3-d] pyrimidin-7-yl] methyl pentanoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Baricitinib Impurity 6 (Stage-3)?

The CAS Registry Number of Baricitinib Impurity 6 (Stage-3) is 1146629-77-7. It is also known as (4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate, [4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate, [4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate.

What is the molecular formula and molecular weight of Baricitinib Impurity 6 (Stage-3)?

Baricitinib Impurity 6 (Stage-3) has the molecular formula C15H17N5O2 and a molecular weight of 299.33 g/mol. Its IUPAC name is [4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate.

What is Baricitinib Impurity 6 (Stage-3) used for?

Baricitinib Impurity 6 (Stage-3) is supplied as a characterised reference material related to Baricitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Baricitinib Impurity 6 (Stage-3) can I order?

We supply Baricitinib Impurity 6 (Stage-3) in Reference Standard (95%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Baricitinib Impurity 6 (Stage-3)?

Yes. Every lot of Baricitinib Impurity 6 (Stage-3) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Baricitinib Impurity 6 (Stage-3) be shipped internationally?

Yes. We export Baricitinib Impurity 6 (Stage-3) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.