1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopro… 116539-56-1

About 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan

1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan is a metabolite or degradation product of Duloxetine carrying the CAS registry number 116539-56-1. Its molecular formula is C8H13NOS and its molecular weight is 171.26 g/mol. Its systematic (IUPAC) name is 3-(methylamino)-1-thiophen-2-ylpropan-1-ol. Alternative names: 3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol and 3-Methylamino-1-(2-thienyl)-1-propanol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Duloxetine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan
Catalogue No.	VQ-025442
CAS Number	116539-56-1
IUPAC name	3-(methylamino)-1-thiophen-2-ylpropan-1-ol
Molecular formula	C₈H₁₃NOS
Molecular weight	171.26 g/mol
Exact mass	171.0718
Grade	Reference Standard
HSN code	38229090
InChIKey	YEJVVFOJMOHFRL-UHFFFAOYSA-N
SMILES	CNCCC(C1=CC=CS1)O
PubChem CID	10214420

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	2 / 3
TPSA	60.5 Å²
Synonyms	3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol, 3-Methylamino-1-(2-thienyl)-1-propanol, N-Methyl-(3-hydroxy-3-(2-thienyl)propyl)amine, 2-Thiophenemethanol, alpha-[2-(methylamino)ethyl]-, 2-Thiophenemethanol, alpha-(2-(methylamino)ethyl)-, (+/-)-3-(N-Methylamino)-1-(2-thienyl)-1-propanol, 1-beta-Hydroxy-1-(2-thienyl)-3-methylaminopropane, (+/-)-1-(2-Thiophenyl)-3-methylamino-1-propanol, 3-(N-Methylamino)-1-(2-thienyl)-1-propanol, (+/-)-, (+/-)-alpha-[2-(methylamino)ethyl]-2-thiophenemethanol, 1-b-Hydroxy-1-(2-thienyl)-3-methylaminopropane, 2-Thiophenemethanol, a-[2-(methylamino)ethyl]-

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan?

The CAS Registry Number of 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan is 116539-56-1. It is also known as 3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol, 3-Methylamino-1-(2-thienyl)-1-propanol, N-Methyl-(3-hydroxy-3-(2-thienyl)propyl)amine.

What is the molecular formula and molecular weight of 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan?

1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan has the molecular formula C8H13NOS and a molecular weight of 171.26 g/mol. Its IUPAC name is 3-(methylamino)-1-thiophen-2-ylpropan-1-ol.

What is 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan used for?

1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan can I order?

We supply 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan?

Yes. Every lot of 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan be shipped internationally?

Yes. 1-Beta-Hydroxy-1-(2-thienyl)-3-methylaminopropan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.