(R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1… 116539-57-2

Name: (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL
Brand: Vaqora Chemicals
SKU: VQ-021210

About (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL

(R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL (CAS 116539-57-2) is an impurity of Duloxetine offered by Vaqora Chemicals. The compound has the formula C8H13NOS, corresponding to a molecular weight of 171.26 g/mol. Systematically, it is named (1R)-3-(methylamino)-1-thiophen-2-ylpropan-1-ol. It is also known as (R)-3-Methylamino-1-(2-thienyl)-1-propanol or (1R)-3-(Methylamino)-1-(2-thienyl)-1-propanol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Duloxetine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL
Catalogue No.	VQ-021210
CAS Number	116539-57-2
IUPAC name	(1R)-3-(methylamino)-1-thiophen-2-ylpropan-1-ol
Molecular formula	C₈H₁₃NOS
Molecular weight	171.26 g/mol
Exact mass	171.0718
Grade	Reference Standard
HSN code	38229090
InChIKey	YEJVVFOJMOHFRL-SSDOTTSWSA-N
SMILES	CNCC[C@H](C1=CC=CS1)O
PubChem CID	10171275

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	2 / 3
TPSA	60.5 Å²
Synonyms	(R)-3-Methylamino-1-(2-thienyl)-1-propanol, (R)-(+)-3-(N-Methylamino)-1-(2-thienyl)-1-propanol, (1R)-3-(Methylamino)-1-(2-thienyl)-1-propanol, 3-(N-Methylamino)-1-(2-thienyl)-1-propanol, (+)-, N-Methyl((R)-3-hydroxy-3-(2-thienyl)propyl)amine, 2-Thiophenemethanol, alpha-(2-(methylamino)ethyl)-, (alphaR)-, 2-Thiophenemethanol, alpha-[2-(methylamino)ethyl]-, (alphaR)-, N-Methyl[(R)-3-hydroxy-3-(2-thienyl)propyl]amine, (S)-3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol, (1R)-3-(methylamino)-1-(2-thienyl)propan-1-ol, (+)-3-(N-methylamino)-1-(2-thienyl)-1-propanol, 2-Thiophenemethanol,

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P260, P264, P270, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P330, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL?

The CAS Registry Number of (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL is 116539-57-2. It is also known as (R)-3-Methylamino-1-(2-thienyl)-1-propanol, (R)-(+)-3-(N-Methylamino)-1-(2-thienyl)-1-propanol, (1R)-3-(Methylamino)-1-(2-thienyl)-1-propanol.

What is the molecular formula and molecular weight of (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL?

(R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL has the molecular formula C8H13NOS and a molecular weight of 171.26 g/mol. Its IUPAC name is (1R)-3-(methylamino)-1-thiophen-2-ylpropan-1-ol.

What is (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL used for?

(R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL can I order?

We supply (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL?

Yes. Every lot of (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL be shipped internationally?

Yes. (R)-3-(Methylamino)-1-(thiophen-2-YL)propan-1-OL is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.