Busulfan-d8

Name: Busulfan-d8
Brand: Vaqora Chemicals
SKU: VQ-029564

About Busulfan-d8

Vaqora Chemicals supplies Busulfan-d8, a stable isotope labelled analogue related to Busulfan registered under CAS number 116653-28-2. Its molecular formula is C6H14O6S2 and its molecular weight is 254.4 g/mol. The IUPAC name is (1,1,2,2,3,3,4,4-octadeuterio-4-methylsulfonyloxybutyl) methanesulfonate. It is also known as (~2~H_8_)Butane-1,4-diyl dimethanesulfonate or TMID-0076.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Busulfan-d8 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Busulfan

View every impurity, metabolite and intermediate we list for Busulfan.

Busulfan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Busulfan-d8
Catalogue No.	VQ-029564
CAS Number	116653-28-2
IUPAC name	(1,1,2,2,3,3,4,4-octadeuterio-4-methylsulfonyloxybutyl) methanesulfonate
Molecular formula	C₆H₁₄O₆S₂
Molecular weight	254.4 g/mol
Exact mass	254.0734
Grade	Reference Standard
HSN code	38229090
InChIKey	COVZYZSDYWQREU-SQUIKQQTSA-N
SMILES	[2H]C([2H])(C([2H])([2H])C([2H])([2H])OS(=O)(=O)C)C([2H])([2H])OS(=O)(=O)C
PubChem CID	45038480

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	0 / 6
TPSA	104 Å²

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H340May cause genetic defects
H350May cause cancer

Precautionary statements: P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Busulfan-d8?

The CAS Registry Number of Busulfan-d8 is 116653-28-2. It is also known as (~2~H_8_)Butane-1,4-diyl dimethanesulfonate, 1,4-Butane-1,1,2,2,3,3,4,4-d8-diol, dimethanesulfonate (9CI), TMID-0076.

What is the molecular formula and molecular weight of Busulfan-d8?

Busulfan-d8 has the molecular formula C6H14O6S2 and a molecular weight of 254.4 g/mol. Its IUPAC name is (1,1,2,2,3,3,4,4-octadeuterio-4-methylsulfonyloxybutyl) methanesulfonate.

What is Busulfan-d8 used for?

Busulfan-d8 is supplied as a characterised reference material related to Busulfan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Busulfan-d8 can I order?

We supply Busulfan-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Busulfan-d8?

Yes. Every lot of Busulfan-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Busulfan-d8 be shipped internationally?

Yes. Busulfan-d8 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.